The nature of meiotic chromosome dynamics and recombination in budding yeast
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microbiology"
DOI: 10.1007/s12275-019-8541-9
Abstract: During meiosis, crossing over allows for the exchange of genes between homologous chromosomes, enabling their segregation and leading to genetic variation in the resulting gametes. Spo11, a topoisomerase-like protein expressed in eukaryotes, and diverse accessory… read more here.
Keywords: budding yeast; meiosis; meiotic chromosome; chromosome dynamics ... See more keywords
The ubiquitin-proteasome system regulates meiotic chromosome organization.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2106902119
Abstract: SignificanceMeiotic crossover recombination is required for faithful chromosome segregation and promotes genetic diversity by reshuffling alleles between parental chromosomes. Meiotic chromosomes are organized into arrays of loops that are anchored to the proteinaceous axes. The… read more here.
Keywords: proteasome system; chromosome organization; chromosome; meiotic chromosome ... See more keywords
Preprint Highlight: DNA damage signaling regulates cohesin stabilization and promotes meiotic chromosome axis morphogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.p22-04-1005
Abstract: Cohesins play an important role in organizing the meiotic chromosome structure, but how cohesins themselves are regulated during this process is not entirely clear. Taking advantage of conditional depletion, point mutations and quantitative immunofluorescence, this… read more here.
Keywords: dna damage; chromosome; meiotic chromosome; cohesin stabilization ... See more keywords
Meiotic chromosome organization and crossover patterns
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac040
Abstract: Abstract Meiosis is the foundation of sexual reproduction, and crossover recombination is one hallmark of meiosis. Crossovers establish the physical connections between homolog chromosomes (homologs) for their proper segregation and exchange DNA between homologs to… read more here.
Keywords: meiotic chromosome; crossover; chromosome organization; crossover patterns ... See more keywords
Excess crossovers impede faithful meiotic chromosome segregation in C. elegans
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009001
Abstract: During meiosis, diploid organisms reduce their chromosome number by half to generate haploid gametes. This process depends on the repair of double strand DNA breaks as crossover recombination events between homologous chromosomes, which hold homologs… read more here.
Keywords: meiotic chromosome; excess crossovers; interfering crossovers; chromosome segregation ... See more keywords
Meiotic Chromosome Contacts as a Plausible Prelude for Robertsonian Translocations
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DOI: 10.3390/genes11040386
Abstract: Robertsonian translocations are common chromosomal alterations. Chromosome variability affects human health and natural evolution. Despite the significance of such mutations, no mechanisms explaining the emergence of such translocations have yet been demonstrated. Several models have… read more here.
Keywords: meiotic chromosome; homologous chromosomes; contacts plausible; robertsonian translocations ... See more keywords
Crossover patterns under meiotic chromosome program.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of andrology"
DOI: 10.4103/aja.aja_86_20
Abstract: Repairing DNA double-strand breaks (DSBs) with homologous chromosomes as templates is the hallmark of meiosis. The critical outcome of meiotic homologous recombination is crossovers, which ensure faithful chromosome segregation and promote genetic diversity of progenies.… read more here.
Keywords: patterns meiotic; meiotic chromosome; crossover; meiotic chromosomes ... See more keywords