Meiotic defects in human oocytes: Potential causes and clinical implications
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DOI: 10.1002/bies.202200135
Abstract: Meiotic defects cause abnormal chromosome segregation leading to aneuploidy in mammalian oocytes. Chromosome segregation is particularly error‐prone in human oocytes, but the mechanisms behind such errors remain unclear. To explain the frequent chromosome segregation errors,… read more here.
Keywords: chromosome segregation; defects human; meiotic defects; human oocytes ... See more keywords
DPFF‐1 transcription factor deficiency causes the aberrant activation of MPK‐1 and meiotic defects in the Caenorhabditis elegans germline
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DOI: 10.1002/dvg.23072
Abstract: The d4 family of transcription factors consists of three members in mammals. DPF1/neuro‐d4 is expressed mainly in neurons and the peripheral nervous system, and is important for brain development. DPF2/requiem/ubi‐d4 is expressed ubiquitously and presumably… read more here.
Keywords: transcription; meiotic defects; dpff transcription; transcription factor ... See more keywords
Velvet antler water extract protects porcine oocytes from lipopolysaccharide-induced meiotic defects.
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DOI: 10.1111/cpr.13392
Abstract: Previous studies have demonstrated that lipopolysaccharide (LPS), as a central toxic factor of gram-negative bacteria, can induce oxidative stress and cellular inflammation to result in the impairment of female fertility in different organisms. Particularly, it… read more here.
Keywords: water extract; antler water; porcine oocytes; meiotic defects ... See more keywords