Gefitinib reduces oocyte quality by disturbing meiotic progression.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology"
DOI: 10.1016/j.tox.2021.152705
Abstract: Gefitinib is a first-line anti-cancer drug for the treatment of advanced non-small cell lung cancer (NSCLC). It has been reported that gefitinib can generate several drug-related adverse effects, including nausea, peripheral edema, decreased appetite and… read more here.
Keywords: gefitinib; meiotic progression; oocyte quality; gefitinib reduces ... See more keywords
Cyclins regulating oocyte meiotic cell cycle progressionâ€
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz143
Abstract: Abstract Oocyte meiotic maturation is a vital and final process in oogenesis. Unlike somatic cells, the oocyte needs to undergo two continuous meiotic divisions (meiosis I and meiosis II) to become a haploid gamete. Notably,… read more here.
Keywords: cyclins regulating; meiotic progression; oocyte meiotic; regulating oocyte ... See more keywords