SGK1 is essential for meiotic resumption in mammalian oocytes.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2022.151210
Abstract: In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic… read more here.
Keywords: sgk1 essential; essential meiotic; resumption; meiotic resumption ... See more keywords
Ste20‐like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13391
Abstract: Ste20‐like kinase (SLK) is involved in cell proliferation and migration in somatic cells. This study aims to explore SLK expression and function in mouse oocyte meiosis. Western blot, immunofluorescence, Co‐immunoprecipitation, drug treatment, cRNA construct and… read more here.
Keywords: meiotic resumption; like kinase; slk; kinase ... See more keywords
Molecular Mechanisms of Prophase I Meiotic Arrest Maintenance and Meiotic Resumption in Mammalian Oocytes
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive Sciences"
DOI: 10.1177/1933719118765974
Abstract: Mechanisms of meiotic prophase I arrest maintenance (germinal vesicle [GV] stage) and meiotic resumption (germinal vesicle breakdown [GVBD] stage) in mammalian oocytes seem to be very complicated. These processes are regulated via multiple molecular cascades… read more here.
Keywords: arrest maintenance; mammalian oocytes; meiotic resumption; resumption ... See more keywords
CENP-T regulates both the G2/M transition and anaphase entry by acting through CDH1 in meiotic oocytes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.238105
Abstract: ABSTRACT Oocyte meiotic maturation failure is one of the major causes for female infertility. Meiotic resumption (the G2/M transition) and progression through metaphase I (MI) are two critical stages of oocyte meiotic maturation. Here, we… read more here.
Keywords: cdh1; anaphase; transition; meiotic resumption ... See more keywords
SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.611503
Abstract: Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study, we deciphered the role… read more here.
Keywords: nppc npr2; shp2; nuclear cytoplasmic; oocyte meiotic ... See more keywords
Intrafollicular Retinoic Acid Signaling Is Important for Luteinizing Hormone-Induced Oocyte Meiotic Resumption
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040946
Abstract: It has been clear that retinoic acid (RA), the most active vitamin A (VA) derivative, plays a central role in governing oocyte meiosis initiation. However, it has not been functionally determined if RA participates in… read more here.
Keywords: resumption; meiotic resumption; oocyte meiotic; retinoic acid ... See more keywords