Independent and cooperative roles of the Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood
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DOI: 10.1002/glia.23602
Abstract: Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserving the integrity of… read more here.
Keywords: mek erk1; myelination; pi3k akt; developmental myelination ... See more keywords
Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR signaling plays both independent and cooperative roles in Schwann cell differentiation, myelination and dysmyelination
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DOI: 10.1002/glia.24049
Abstract: Multiple signals are involved in the regulation of developmental myelination by Schwann cells and in the maintenance of a normal myelin homeostasis throughout adult life, preserving the integrity of the axons in the PNS. Recent… read more here.
Keywords: erk1 mapk; mek erk1; mtor; myelination ... See more keywords
Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway
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DOI: 10.1007/s12031-017-0944-7
Abstract: Subarachnoid hemorrhage (SAH) is a serious clinical condition where leakage of blood into the subarachnoid space causes an acute rise in intracranial pressure and reduces cerebral blood flow, which may lead to delayed cerebral ischemia… read more here.
Keywords: mek erk1; cerebral arteries; erk1 pathway; subarachnoid hemorrhage ... See more keywords