Dioscorea nipponica Makino Relieves Ovalbumin-Induced Asthma in Mice through Regulating RKIP-Mediated Raf-1/MEK/MAPK/ERK Signaling Pathway
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DOI: 10.1155/2022/8077058
Abstract: Purpose Dioscorea nipponica Makino (DNM) is a traditional herb with multiple medicinal functions. This study is aimed at exploring the therapeutic effects of DNM on asthma and the underlying mechanisms involving RKIP-mediated MAPK signaling pathway.… read more here.
Keywords: raf mek; rkip; mek mapk; mapk erk ... See more keywords
Abstract 2144: Mutations in ERBB4 may account for clinical resistance of melanomas to inhibitors of the RAS/RAF/MEK/MAPK pathway
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DOI: 10.1158/1538-7445.sabcs18-2144
Abstract: Introduction: Despite advancements made in the treatment of metastatic melanoma, the 5-year survival rate remains about 20%. The high mortality rate is thought to be due to there being no other clinically actionable targets other… read more here.
Keywords: ras raf; mek mapk; mapk pathway; melanoma ... See more keywords