Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of resistance to antiestrogen-induced BimEL dependent apoptosis in ER+ breast cancer cells
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DOI: 10.3892/ijo.2022.5468
Abstract: The epidermal growth factor receptor (EGFR) is commonly upregulated in multiple cancer types, including breast cancer. In the present study, evidence is provided in support of the premise that upregulation of the EGFR/MEK1/MAPK1/2 signaling axis… read more here.
Keywords: cancer cells; antiestrogen; breast cancer; mek1 mapk1 ... See more keywords