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   Articles with "mel" as a keyword



Melittin‐Loaded Multifunctional Nanozyme for Ulcerative Colitis Treatment via Enzyme‐Immunotherapy and Ferroptosis Inhibition

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202503374

Abstract: In ulcerative colitis (UC), oxidative stress (OS) and iron overload disrupt immune homeostasis and intestinal barrier function, exacerbating inflammation through effects on macrophages and intestinal epithelial cells (IECs). Reversing macrophage‐driven inflammation and restoring homeostasis of… read more here.

Keywords: pda mel; mel; homeostasis; ulcerative colitis ... See more keywords

Melatonin Modulates Glucose Metabolism Reprogramming via Targeting G6PD to Alleviate Lead‐Induced Hepatocytes Pyroptosis in Common Carp (Cyprinus carpio L.)

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202501041

Abstract: Lead (Pb) is a prevalent toxic contaminant that accumulates in freshwater ecosystems, posing severe toxicity to non‐target species such as fish and contributing to the pathogenesis of liver disease. Melatonin (Mel) is a well‐known natural… read more here.

Keywords: mel; glucose metabolism; melatonin; hepatocytes pyroptosis ... See more keywords

Melatonin is effective in attenuating cisplatin-induced neurotoxicity.

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recommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"

DOI: 10.1002/jbt.23075

Abstract: Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis of neurotoxicity… read more here.

Keywords: vehicle; mel; cis; induced neurotoxicity ... See more keywords

The effect of melatonin on glycoprotein levels and oxidative liver injury in experimental diabetes

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recommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23268

Abstract: In this present study, the duration of melatonin (Mel) administered to diabetic rats was prolonged so as to examine its effects on the biochemical liver parameters of diabetic rats. In the experiment, Male Sprague Dawley… read more here.

Keywords: diabetic rats; effect; mel; diabetic mel ... See more keywords

Biological activity of mannosylerythritol lipids on the mammalian cells.

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recommendations! Published in 2020 at "Applied microbiology and biotechnology"

DOI: 10.1007/s00253-020-10857-9

Abstract: Mannosylerythritol lipids (MEL) are glycolipids mainly produced by pseudo-yeasts. These molecules present remarkable biological activities widely explored in many fields, including medicine, pharmaceuticals, and cosmetics. This review presents the main biological activity of MEL on… read more here.

Keywords: biological activity; mel; mammalian cells; mannosylerythritol lipids ... See more keywords
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Production of Mannosylerythritol Lipids (MELs) to be Used as Antimicrobial Agents Against S. aureus ATCC 6538

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recommendations! Published in 2020 at "Current Microbiology"

DOI: 10.1007/s00284-020-01927-2

Abstract: Antimicrobial resistance (AMR) is a current major health issue, both for the high rates of resistance observed in bacteria that cause common infections and for the complexity of the consequences of AMR. Pathogens like Staphylococcus… read more here.

Keywords: lipids mels; usepackage; aureus atcc; atcc 6538 ... See more keywords

Effects of Diclofenac Versus Meloxicam in Pentylenetetrazol-Kindled Mice

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recommendations! Published in 2020 at "Neurochemical Research"

DOI: 10.1007/s11064-020-03054-7

Abstract: Epilepsy comes after stroke as the most common chronic neurological disorder worldwide. Inflammation enhances neuronal hyperexcitability that could provide a background setting for the development of epilepsy. The aim of this study was to assess… read more here.

Keywords: kindled mice; val dic; val; val mel ... See more keywords

Dual Effect of Melatonin in Fetal Brain: Structural and Cellular Implications in a Rabbit Model of Intrauterine Growth Restriction

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recommendations! Published in 2025 at "Molecular Neurobiology"

DOI: 10.1007/s12035-025-05032-y

Abstract: Intrauterine growth restriction (IUGR) is a condition in which the fetus fails to reach its genetic growth potential, often resulting in neurodevelopmental alterations. This study investigates the neuroprotective potential of gestational melatonin (MEL) treatment using… read more here.

Keywords: mel; brain; rabbit model; intrauterine growth ... See more keywords

Curative potential of fludarabine, melphalan, and non-myeloablative dosage of busulfan in elderly patients with myeloid malignancy

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recommendations! Published in 2019 at "International Journal of Hematology"

DOI: 10.1007/s12185-019-02763-2

Abstract: Although the combination of fludarabine and high-dose melphalan (FLU/MEL) has been widely used in allogeneic stem cell transplantation, high-dose MEL causes life-threatening adverse events, especially in elderly patients. To reduce the toxicity of MEL without… read more here.

Keywords: curative potential; elderly patients; non myeloablative; mel ... See more keywords

Patients atteints de mélanome sans primitif retrouvé de la base nationale RIC-Mel

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recommendations! Published in 2017 at "Annales De Dermatologie Et De Venereologie"

DOI: 10.1016/j.annder.2017.09.513

Abstract: Introduction Un melanome de primitif inconnu (MPI) est defini comme un melanome diagnostique sur une lesion secondaire sans lesion primitive retrouvee et est considere d’emblee comme un melanome metastatique. La prise en charge des patients… read more here.

Keywords: patients mpc; ric mel; patients mpi; les patients ... See more keywords

Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS.

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recommendations! Published in 2017 at "Bone"

DOI: 10.1016/j.bone.2017.04.010

Abstract: Melorheostosis (MEL) is the rare sporadic dysostosis characterized by monostotic or polyostotic osteosclerosis and hyperostosis often distributed in a sclerotomal pattern. The prevailing hypothesis for MEL invokes postzygotic mosaicism. Sometimes scleroderma-like skin changes, considered a… read more here.

Keywords: implicates postzygotic; exome sequencing; mosaicism; postzygotic mosaicism ... See more keywords