Glycerol inhibition of melanin biosynthesis in the environmental Aeromonas salmonicida 34melT
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9545-9
Abstract: The environmental strain Aeromonas salmonicida subsp. pectinolytica 34melT produces abundant melanin through the homogentisate pathway in several culture media, but unexpectedly not when grown in a medium containing glycerol. Using this observation as a starting… read more here.
Keywords: melanin; melanin synthesis; inhibition; aeromonas salmonicida ... See more keywords
Transcriptome and metabolite analysis reveals key genes for melanin synthesis during the development of Zanthoxylum bungeanum seeds
Sign Up to like & getrecommendations! Published in 2021 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2021.113419
Abstract: Abstract Melanin is a broad term for a family of complex organic macromolecules that contain phenol or indole groups. Melanins are found in animals, plants, and microorganisms and are widely used in medicine, food, and… read more here.
Keywords: transcriptome metabolite; synthesis; seed; melanin ... See more keywords
Spatiotemporal Control of Melanin Synthesis in Liquid Droplets.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c21006
Abstract: Melanins are natural biopolymers that have remarkable properties including UV-protection, coloration, and antioxidant activity. Their biosynthesis is regulated both spatially and temporally and involves supramolecular templating and compartmentalization of enzymes and reactants within specialized organelles… read more here.
Keywords: methodology; control; liquid droplets; melanin ... See more keywords
Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H2O2-induced oxidative stress
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra09786k
Abstract: Vitiligo is an intriguing depigmentation disorder that affects about 0.5–2% of the world population. read more here.
Keywords: sodium tanshinone; iia silate; increases melanin; tanshinone iia ... See more keywords
Indications of symbiotic state influencing melanin-synthesis immune response in the facultative coral Astrangia poculata.
Sign Up to like & getrecommendations! Published in 2022 at "Diseases of aquatic organisms"
DOI: 10.3354/dao03695
Abstract: Increased ocean warming is causing detrimental impacts to tropical corals worldwide. Compounding the effects of heat stress, incidences of tropical coral disease have risen concurrently. While tropical coral responses to these impacts are well studied,… read more here.
Keywords: melanin; melanin synthesis; immune response; response ... See more keywords
The Molecular Properties and Roles of Pannier in Harmonia axyridis’s Metamorphosis and Melanin Synthesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.909258
Abstract: The GATA transcription factor Pannier is identified as the major regulatory gene in color pattern formation in the Asian multi-colored ladybird beetle (Harmonia axyridis). however, the mechanisms of Pannier in regulating melanin synthesis and development… read more here.
Keywords: hapnr; axyridis; hapnr hapnr; melanin synthesis ... See more keywords
Mangiferin Affects Melanin Synthesis by an Influence on Tyrosinase: Inhibition, Mechanism of Action and Molecular Docking Studies
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12051016
Abstract: Mangiferin is a strong antioxidant that presents a wide range of biological activities. The aim of this study was to evaluate, for the first time, the influence of mangiferin on tyrosinase, an enzyme responsible for… read more here.
Keywords: molecular docking; inhibition; tyrosinase; melanin synthesis ... See more keywords
Up- or Downregulation of Melanin Synthesis Using Amino Acids, Peptides, and Their Analogs
Sign Up to like & getrecommendations! Published in 2020 at "Biomedicines"
DOI: 10.3390/biomedicines8090322
Abstract: Harmonious synthesis and distribution of melanin in the skin contribute to the expression of beauty and the maintenance of health. When skin pigmentary disorders occur because of internal or external factors or, when there is… read more here.
Keywords: amino acids; melanin; melanin synthesis; acids peptides ... See more keywords
The Organogermanium Compound THGP Suppresses Melanin Synthesis via Complex Formation with L-DOPA on Mushroom Tyrosinase and in B16 4A5 Melanoma Cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20194785
Abstract: The organogermanium compound 3-(trihydroxygermyl)propanoic acid (THGP) has various biological activities. We previously reported that THGP forms a complex with cis-diol structures. L-3,4-Dihydroxyphenylalanine (L-DOPA), a precursor of melanin, contains a cis-diol structure in its catechol skeleton,… read more here.
Keywords: thgp; dopa; melanin synthesis; tyrosinase ... See more keywords
Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)-N-(2-hydroxyethyl)-N-Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21134589
Abstract: The aim of this study was to identify novel antimelanogenic drugs from an epigenetic screening library containing various modulators targeting DNA methyltransferases, histone deacetylases, and other related enzymes/proteins. Of 141 drugs tested, K8 (4-((hydroxyamino)carbonyl)-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide; HPOB)… read more here.
Keywords: hydroxyethyl phenyl; melanin synthesis; carbonyl hydroxyethyl; hydroxyamino carbonyl ... See more keywords
Contribution of the Tyrosinase (MoTyr) to Melanin Synthesis, Conidiogenesis, Appressorium Development, and Pathogenicity in Magnaporthe oryzae
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9030311
Abstract: Dihydroxynapthalene-(DHN) and L-dihydroxyphenylalanine (L-DOPA) are two types of dominant melanin in fungi. Fungal melanins with versatile functions are frequently associated with pathogenicity and stress tolerance. In rice blast fungus, Magnaporthe oryzae, DHN melanin is essential… read more here.
Keywords: melanin; motyr; magnaporthe oryzae; pathogenicity ... See more keywords