Articles with "melanocortin signalling" as a keyword



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Heterozygous Genetic Variants in Autosomal Recessive Genes of the Leptin-Melanocortin Signalling Pathway Are Associated With the Development of Childhood Obesity

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.832911

Abstract: Monogenic obesity is a severe, genetically determined disorder that affects up to 1/1000 newborns. Recent reports on potential new therapeutics and innovative clinical approaches have highlighted the need for early identification of individuals with rare… read more here.

Keywords: genetic variants; genes leptin; melanocortin signalling; leptin melanocortin ... See more keywords