A critical update on the leptin‐melanocortin system
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15765
Abstract: The discovery of leptin in 1994 was an “eureka moment” in the field of neurometabolism that provided new opportunities to better understand the central control of energy balance and glucose metabolism. Rapidly, a prevalent model… read more here.
Keywords: melanocortin system; leptin; leptin melanocortin; pomc neurons ... See more keywords
Role of the Melanocortin System in the Central Regulation of Cardiovascular Functions
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DOI: 10.3389/fphys.2021.725709
Abstract: Increasing evidence indicates that the melanocortin system is not only a central player in energy homeostasis, food intake and glucose level regulation, but also in the modulation of cardiovascular functions, such as blood pressure and… read more here.
Keywords: melanocortin system; system; central regulation; cardiovascular functions ... See more keywords
The Melanocortin System: A Promising Target for the Development of New Antidepressant Drugs
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DOI: 10.3390/ijms24076664
Abstract: Major depression is one of the most prevalent mental disorders, causing significant human suffering and socioeconomic loss. Since conventional antidepressants are not sufficiently effective, there is an urgent need to develop new antidepressant medications. Despite… read more here.
Keywords: system; melanocortin system; depression; new antidepressant ... See more keywords
Polymorphisms of leptin-melanocortin system genes associated with obesity in an adult population from Barranquilla
Sign Up to like & getrecommendations! Published in 2020 at "Biomedica : revista del Instituto Nacional de Salud"
DOI: 10.7705/biomedica.4827
Abstract: Introduction: Obesity is considered a serious public health problem. Efforts have been directed to search for candidate genes such as LEP, LEPR, and MC4R involved in the leptin-melanocortin system. The neuroendocrine regulation of these genes… read more here.
Keywords: melanocortin system; leptin melanocortin; mc4r rs17782313; obesity ... See more keywords