Laser-assisted drug delivery of synthetic alpha melanocyte stimulating hormone and L-tyrosine leads to increased pigmentation area and expression of melanogenesis genes in a porcine hypertrophic scar model.
Sign Up to like & getrecommendations! Published in 2023 at "Lasers in surgery and medicine"
DOI: 10.1002/lsm.23663
Abstract: One symptom of hypertrophic scar (HTS) that can develop after burn injury is dyschromia with hyper‐ and hypopigmentation. There are limited treatments for these conditions. Previously, we showed there is no expression of alpha melanocyte… read more here.
Keywords: assisted drug; hypertrophic scar; alpha melanocyte; stimulating hormone ... See more keywords
The anorexigenic effect of beta-melanocyte-stimulating hormone involves corticotrophin-releasing factor and mesotocin in birds
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.135282
Abstract: Beta-melanocyte-stimulating hormone (β-MSH), when centrally injected, induces anorexigenic effects in rodents and chickens but its mechanism remains unclear. Thus, the primary goal of this research was to elucidate the hypothalamic mechanism using chickens. Intracerebroventricular injection… read more here.
Keywords: melanocyte stimulating; hormone; corticotrophin releasing; receptor ... See more keywords
Relationship between α‐melanocyte stimulating hormone levels and therapeutic outcome of melanocyte transplantation and phototherapy in non‐segmental patients with vitiligo: A prospective study
Sign Up to like & getrecommendations! Published in 2018 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.12769
Abstract: 1. Reid JD, Kommareddi S, Lankerani M et al. Chronic expanding hematomas. A clinicopathologic entity. JAMA 1980; 244: 2441–2. 2. Burgert-Lon CE, Riddle ND, Lackman RD et al. Angiosarcoma arising in chronic expanding hematoma: five… read more here.
Keywords: relationship melanocyte; stimulating hormone; chronic expanding; expanding hematoma ... See more keywords
Risks of unregulated use of alpha‐melanocyte‐stimulating hormone analogues: a review
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Dermatology"
DOI: 10.1111/ijd.13585
Abstract: Recently, the unregulated use of untested synthetic alpha‐melanocyte‐stimulating hormone (α‐MSH) analogues, commonly known as melanotan I and II, appears to have increased. These analogues are primarily used for their tan‐stimulating effects. Dermatologists see many patients… read more here.
Keywords: use; risks unregulated; melanocyte stimulating; unregulated use ... See more keywords
Short-term effects of α-melanocyte-stimulating hormone in three distinct melanin-pigmented cell types of Anura.
Sign Up to like & getrecommendations! Published in 2023 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202320211581
Abstract: Ectothermic animals present melanin-containing cells in their integument and viscera. Besides cutaneous melanophores, amphibians have melanomacrophages in the hepatic parenchyma and melanocytes in the viscera, which are also present in their testicular stroma. The native… read more here.
Keywords: hormone; melanin; term effects; stimulating hormone ... See more keywords
7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.577284
Abstract: 7,3′,4′-Trihydroxyisoflavone (7,3′,4′-THIF) is a metabolite of daidzein which is a representative isoflavone found in soybean. Recent studies suggested that 7,3′,4′-THIF exerts a hypopigmentary effect in B16F10 cells, however, its underlying molecular mechanisms and specific target… read more here.
Keywords: msh induced; daidzein; melanocortin receptor; targeting melanocortin ... See more keywords
Gamma-Aminobutyric Acid (GABA) Inhibits α-Melanocyte-Stimulating Hormone-Induced Melanogenesis through GABAA and GABAB Receptors
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22158257
Abstract: Gamma-aminobutyric acid (GABA) is considered the primary inhibitory neurotransmitter in the human cortex. However, whether GABA regulates melanogenesis has not been comprehensively elucidated. In this study, we reveal that GABA (20 mM) significantly inhibited α-melanocyte-stimulating… read more here.
Keywords: gamma aminobutyric; gabab; acid gaba; gaba ... See more keywords
Pinostrobin Suppresses the α-Melanocyte-Stimulating Hormone-Induced Melanogenic Signaling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010821
Abstract: Pinostrobin is a dietary flavonoid found in several plants that possesses pharmacological properties, such as anti-cancer, anti-virus, antioxidant, anti-ulcer, and anti-aromatase effects. However, it is unclear if pinostrobin exerts anti-melanogenic properties and, if so, what… read more here.
Keywords: signaling pathway; pinostrobin suppresses; pinostrobin; stimulating hormone ... See more keywords
Construction of a Tandem Repeat Peptide Sequence with Pepsin Cutting Sites to Produce Recombinant α-Melanocyte-Stimulating Hormone
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26206207
Abstract: The production of α-melanocyte-stimulating hormone (α-MSH), a peptide hormone composed of 13 amino acids, is attempted by recombinant expression using E. coli as the host. To achieve this aim, a synthetic gene containing eight tandem… read more here.
Keywords: hormone; pepsin; tandem repeat; msh ... See more keywords