Nevus, melanoma, or something else? Mesenchymal neoplasms with melanocytic differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.14232
Abstract: The overwhelming majority of cutaneous neoplasms with melanocytic differentiation are nevi, melanomas, or less commonly melanocytomas. Nevertheless, there is also a group of mesenchymal neoplasms with genuine melanocytic differentiation which can create diagnostic difficulties with… read more here.
Keywords: mesenchymal neoplasms; melanoma something; nevus melanoma; melanocytic differentiation ... See more keywords
Clear cell tumor with melanocytic differentiation and MITF::CREM translocation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cutaneous pathology"
DOI: 10.1111/cup.14427
Abstract: In addition to melanoma, a large and diverse family of tumors shows melanocytic differentiation. The best characterized member of this family is clear cell sarcoma, which is characterized by EWSR1::ATF1 and EWSR1::CREB1 fusions. These fusions… read more here.
Keywords: crem; melanocytic differentiation; clear cell; differentiation ... See more keywords
Eribulin Suppresses Clear Cell Sarcoma Growth by Inhibiting Cell Proliferation and Inducing Melanocytic Differentiation Both Directly and Via Vascular Remodeling
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-19-0358
Abstract: Clear cell sarcoma (CCS) is a rare but chemotherapy-resistant and often fatal high-grade soft-tissue sarcoma (STS) characterized by melanocytic differentiation under control of microphthalmia-associated transcription factor (MITF). Eribulin mesilate (eribulin) is a mechanistically unique microtubule… read more here.
Keywords: sarcoma; cell proliferation; differentiation; cell ... See more keywords