Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202505469
Abstract: Microbial genetic variation plays a crucial role in shaping host‐microbe interactions; however, its impact on healthy aging remains largely unexplored. This study investigates how genetic variations in gut‐residing Saccharomyces cerevisiae affect the health and lifespan… read more here.
Keywords: microbial genetic; host; drosophila melanogaster; melanogaster ... See more keywords
"Scent of a fruit fly": Cuticular chemoprofiles after mating in differently fed Drosophila melanogaster (Diptera: Drosophilidae) strains.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21866
Abstract: In the world of complex smells in natural environment, feeding and mating represent two important olfactory-guided behaviors in Drosophila melanogaster (Diptera: Drosophilidae). Diet affects the chemoprofile composition of the individuals, which, indirectly, may significantly affect… read more here.
Keywords: melanogaster diptera; differently fed; diptera drosophilidae; melanogaster ... See more keywords
Exposure to boron trioxide nanoparticles and ions cause oxidative stress, DNA damage, and phenotypic alterations in Drosophila melanogaster as an in vivo model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4363
Abstract: Boron trioxide nanoparticles (B2O3 NPs) have recently been widely used in a range of applications including electronic device technologies, acousto‐optic apparatus fields, and as nanopowder for the production of special glasses. We propose Drosophila melanogaster… read more here.
Keywords: dna damage; model; melanogaster; b2o3 nps ... See more keywords
Azadirachtin effects on mating success, gametic abnormalities and progeny survival in Drosophila melanogaster (Diptera).
Sign Up to like & getrecommendations! Published in 2018 at "Pest management science"
DOI: 10.1002/ps.4678
Abstract: BACKGROUND Azadirachtin is a prominent natural pesticide and represents an alternative to conventional insecticides. It has been successfully used against insect pests. However, its effects on reproduction require further analysis. Here we investigated lethal and… read more here.
Keywords: azadirachtin effects; melanogaster; azadirachtin; drosophila melanogaster ... See more keywords
Silver nanoparticle–induced developmental inhibition of Drosophila melanogaster accompanies disruption of genetic material of larval neural stem cells and non-neuronal cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-019-7630-x
Abstract: A few studies had determined the effects of silver nanoparticles on the development of Drosophila melanogaster. However, none had addressed its genotoxic effects on specific larval cells of the fly in details. This study was… read more here.
Keywords: melanogaster; drosophila melanogaster; silver nanoparticle; developmental inhibition ... See more keywords
LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress
Sign Up to like & getrecommendations! Published in 2024 at "Neurochemical Research"
DOI: 10.1007/s11064-024-04141-9
Abstract: Parkinson’s disease (PD) is a complex multifactorial progressive neurodegenerative disease characterized by locomotor alteration due to the specific deterioration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SNpc). Mounting evidence shows that human… read more here.
Keywords: drosophila melanogaster; melanogaster; oxidative stress; inhibitor 06447475 ... See more keywords
Curcuma longa L. Prevents the Loss of β-Tubulin in the Brain and Maintains Healthy Aging in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Neurobiology"
DOI: 10.1007/s12035-021-02701-6
Abstract: Loss of tubulin is associated with neurodegeneration and brain aging. Turmeric (Curcuma longa L.) has frequently been employed as a spice in curry and traditional medications in the Indian subcontinent to attain longevity and better… read more here.
Keywords: curcuma longa; loss; melanogaster; loss tubulin ... See more keywords
Effects of long-term and low-concentration exposures of benzene and formaldehyde on mortality of Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental pollution"
DOI: 10.1016/j.envpol.2022.118924
Abstract: Single-chemical thresholds cannot comprehensively evaluate the risk of chemical mixture exposure in indoor air. Moreover, a large number of researches have focused on short-term and high-concentration co-exposure scenarios related to different species, based on diverse… read more here.
Keywords: exposure; concentration; long term; term ... See more keywords
Timed Knickkopf function is essential for wing cuticle formation in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2017 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2017.08.003
Abstract: The insect cuticle is an extracellular matrix that consists of the polysaccharide chitin, proteins, lipids and organic molecules that are arranged in distinct horizontal layers. In Drosophila melanogaster, these layers are not formed sequentially, but,… read more here.
Keywords: melanogaster; cuticle formation; function; cuticle ... See more keywords
MicroRNA miR-8 promotes cell growth of corpus allatum and juvenile hormone biosynthesis independent of insulin/IGF signaling in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2021 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2021.103611
Abstract: The Drosophila melanogaster corpus allatum (CA) produces and releases three types of sesquiterpenoid hormones, including juvenile hormone III bisepoxide (JHB3), juvenile hormone III (JH III), and methyl farnesoate (MF). JH biosynthesis involves multiple discrete enzymatic… read more here.
Keywords: hormone; melanogaster; biosynthesis; juvenile hormone ... See more keywords
Ameliorative role of diets fortified with Curcumin in a Drosophila melanogaster model of aluminum chloride-induced neurotoxicity
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.104035
Abstract: Abstract Aluminum is an environmental and industrial neurotoxicant known to induce oxidative damage and inflammation in tissues. Curcumin is a polyphenol with antioxidant and anti-inflammatory properties. Here, we evaluated Curcumin’s protective role in Aluminum Chloride… read more here.
Keywords: melanogaster; aluminum chloride; alcl3 induced; role ... See more keywords