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Published in 2017 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-017-1717-4
Abstract: Melanocytes play an important role in maintaining epidermal homeostasis by producing melanin and protecting the skin from harmful environmental factors. However, excessive up- or down-regulation of melanin production often causes hyper- or hypo-pigmented disorders, respectively,…
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Keywords:
activity;
melanogenic activity;
anti melanogenic;
synergistic effect ... See more keywords
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Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.06.021
Abstract: Skin pigmentation involves multiple processes, including melanin synthesis, transport, and melanosome release. Melanin content determines skin color and protects against UV radiation-induced damage. Autophagy is a cooperative process between autophagosomes and lysosomes that degrades cellular…
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Keywords:
rhizoma arisaematis;
b16f1 cells;
melanogenic activity;
schaftoside ... See more keywords
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Published in 2017 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2017.03.011
Abstract: BACKGROUND Microphthalmia-associated transcription factor (MITF) suppresses the expression of enzymes controlling the production of melanin. Phytosphingosine is a well-known cosmetic agent, but its anti-melanogenic activity and mechanism of action remain unclear. OBJECTIVE This study was…
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Keywords:
transcription;
mitf;
phytosphingosine;
melanogenic activity ... See more keywords
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Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14569
Abstract: Skin hyperpigmentation is commonly treated by topical drug application. Several naturally occurring compounds exhibit attractive biological effects including anti‐melanogenic activity. Chemically modified derivatives of those compounds are expected to be more efficient. However, efficacy and…
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Keywords:
tiered approach;
activity;
activity trans;
anti melanogenic ... See more keywords