Improvement of Genetic Testing for Cutaneous Melanoma in Countries With Low to Moderate Incidence: The Rule of 2 vs the Rule of 3
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DOI: 10.1001/jamadermatol.2017.2926
Abstract: Importance Genetic testing for melanoma-prone mutation in France, a country with low to moderate incidence of melanoma, is proposed in cases with 2 invasive cutaneous melanomas and/or related cancers in the same patient, or in… read more here.
Keywords: melanoma; genetic testing; low moderate; moderate incidence ... See more keywords
Sensitivity of Preference-Based Quality-of-Life Measures for Economic Evaluations in Early-Stage Melanoma
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DOI: 10.1001/jamadermatol.2017.4701
Abstract: Importance The diagnosis of a life-threatening disease like melanoma can affect all aspects of a person’s life, including health-related quality of life (HRQOL) and psychological aspects of melanoma such as fear of cancer recurrence (FCR).… read more here.
Keywords: melanoma; utility; sensitivity; fact ... See more keywords
Accuracy of Dermoscopic Criteria for the Diagnosis of Melanoma In Situ
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DOI: 10.1001/jamadermatol.2017.6447
Abstract: Importance The accuracy of melanoma-specific dermoscopic criteria has been tested mainly in studies including invasive tumors. Scarce evidence exists on the usefulness of these criteria for the diagnosis of melanoma in situ (MIS). Objective To… read more here.
Keywords: melanoma; diagnosis; dermoscopic; dermoscopic criteria ... See more keywords
Association of Quality of Life With Surgical Excision of Early-Stage Melanoma of the Head and Neck
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DOI: 10.1001/jamadermatol.2018.3409
Abstract: Importance Surgical excision is the standard-of-care treatment for Tis and T1a melanomas of the head and neck. Currently, however, the association of diagnosis and surgical treatment of these typically slowly progressive and nonfatal melanomas with… read more here.
Keywords: head; melanoma; year; excision ... See more keywords
Accuracy of Computer-Aided Diagnosis of Melanoma: A Meta-analysis.
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DOI: 10.1001/jamadermatol.2019.1375
Abstract: Importance The recent advances in the field of machine learning have raised expectations that computer-aided diagnosis will become the standard for the diagnosis of melanoma. Objective To critically review the current literature and compare the… read more here.
Keywords: melanoma; diagnosis; accuracy; aided diagnosis ... See more keywords
Efficiency of Detecting New Primary Melanoma Among Individuals Treated in a High-risk Clinic for Skin Surveillance.
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DOI: 10.1001/jamadermatol.2020.5651
Abstract: Importance A previous single-center study observed fewer excisions, lower health care costs, thinner melanomas, and better quality of life when surveillance of high-risk patients was conducted in a melanoma dermatology clinic with a structured surveillance… read more here.
Keywords: melanoma; dermatology; surveillance; high risk ... See more keywords
Association of Treatment Facility Characteristics With Overall Survival After Mohs Micrographic Surgery for T1a-T2a Invasive Melanoma.
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DOI: 10.1001/jamadermatol.2021.0023
Abstract: Importance Early-stage melanoma, among the most common cancers in the US, is typically treated with wide local excision. However, recent advances in immunohistochemistry have led to an increasing number of these cases being excised via… read more here.
Keywords: melanoma; treatment; mohs micrographic; t1a t2a ... See more keywords
Estimating Overdiagnosis of Melanoma Using Trends Among Black and White Patients in the US.
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DOI: 10.1001/jamadermatol.2022.0139
Abstract: Importance The incidence of cutaneous melanoma has been rising rapidly among White patients in the US; however, a commensurate increase in mortality due to melanoma has not been observed. These trends suggest overdiagnosis is occurring.… read more here.
Keywords: melanoma; incidence; among white; mortality ... See more keywords
Dermatopathologist Perceptions of Overdiagnosis of Melanocytic Skin Lesions and Association With Diagnostic Behaviors.
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DOI: 10.1001/jamadermatol.2022.0489
Abstract: Importance Despite evidence of overdiagnosis of in situ and invasive melanoma, neither the perceptions of practicing dermatopathologists about overdiagnosis nor possible associations between perceptions of overdiagnosis and diagnostic practices have been studied. Objective To examine… read more here.
Keywords: perceptions overdiagnosis; melanoma; atypical nevi; melanocytic skin ... See more keywords
Association Between Low-Dose Methotrexate Exposure and Melanoma: A Systematic Review and Meta-analysis.
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DOI: 10.1001/jamadermatol.2022.3337
Abstract: Importance Methotrexate is widely used for the treatment of inflammatory disorders, including rheumatoid arthritis. Studies suggest that methotrexate may be associated with an increased risk of melanoma. Objective To determine whether methotrexate exposure is associated… read more here.
Keywords: melanoma; methotrexate; methotrexate exposure; risk ... See more keywords
Association Between Metastatic Melanoma Response to Checkpoint Inhibitor Therapy and Tumor-Infiltrating Lymphocyte Classification on Primary Cutaneous Melanoma Biopsies.
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DOI: 10.1001/jamadermatol.2022.4959
Abstract: This cohort study examines the association between tumor-infiltrating lymphocyte classification and disease progression among patients with metastatic primary cutaneous melanoma receiving checkpoint inhibitor therapy. read more here.
Keywords: tumor infiltrating; melanoma; primary cutaneous; cutaneous melanoma ... See more keywords