Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12151
Abstract: Melanomas harboring BRAF mutation (V600E) are known to recur frequently following treatment with BRAF inhibitors (BRAFi) despite a high initial response rate. Our previous study has uncovered that BRAFi‐resistant melanoma (BR) cells are vulnerable to… read more here.
Keywords: melanoma cells; arginine deprivation; degradation ampk;
Focal adhesion alterations in G0‐positive melanoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5510
Abstract: Melanoma is a highly heterogeneous malignant tumor that exhibits various forms of drug resistance. Recently, reversal transition of cancer cells to the G0 phase of the cell cycle under the influence of therapeutic drugs has… read more here.
Keywords: adhesion alterations; alterations positive; melanoma; positive melanoma ... See more keywords
Direct RIG‐I activation in human NK cells induces TRAIL‐dependent cytotoxicity toward autologous melanoma cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.31874
Abstract: Activation of the innate immune receptor retinoic acid‐inducible gene I (RIG‐I) by its specific ligand 5′‐triphosphate RNA (3pRNA) triggers anti‐tumor immunity, which is dependent on natural killer (NK) cell activation and cytokine induction. However, to… read more here.
Keywords: rig activation; rig; melanoma cells; activation ... See more keywords
PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.34947
Abstract: Metastatic melanoma is still a difficult‐to‐treat cancer type owing to its frequent resistance mechanisms to targeted and immunotherapy. Therefore, we aimed to unravel novel therapeutic strategies for melanoma patients. Preclinical and clinical studies show that… read more here.
Keywords: parp1; parp1 expression; melanoma patients; melanoma cells ... See more keywords
A heterodimer of hemoglobin identifies theranostic targets on brain‐metastasizing melanoma cells
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Cancer"
DOI: 10.1002/ijc.35458
Abstract: Cancer microenvironments encompass both cancer‐promoting and cancer‐restraining factors. If these factors cancel each other, cancer dormancy may ensue. In search of microenvironmental factors that keep dormant lung‐metastasizing neuroblastoma cells and brain‐metastasizing melanoma cells (BMMC) in… read more here.
Keywords: cancer; metastasizing melanoma; bmmc; melanoma cells ... See more keywords
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells
Sign Up to like & getrecommendations! Published in 2020 at "IUBMB Life"
DOI: 10.1002/iub.2227
Abstract: Malignant melanoma is one of the most aggressive human tumor types, mainly due to its high invasion capability, metastatic properties, and the absence of effective treatments. Glycosylation serves a pivotal role in the migration and… read more here.
Keywords: melanoma; invasion; melanoma cells; expression ... See more keywords
Biosafety and differentially expressed genes analysis of melanoma cells treated with cold atmospheric plasma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202100403
Abstract: Cold atmospheric plasma (CAP) has attracted increasing attention due to its anti‐bacterial and anti‐tumor effects. Melanoma is an aggressive malignancy with increasing incidence rate and poor prognosis. Evaluating cell viability, apoptosis rate and reactive species… read more here.
Keywords: cold atmospheric; atmospheric plasma; cap; melanoma cells ... See more keywords
Biological Effects of Intense Terahertz Waves at 2.88 THz on Breast Cancer and Melanoma Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of biophotonics"
DOI: 10.1002/jbio.202500307
Abstract: Current research has shown that terahertz (THz) waves can induce some bioeffects on certain human tumor cells. These effects are significant for potential applications in future tumor treatments. However, there are limited reports on the… read more here.
Keywords: cancer; breast cancer; thz; melanoma cells ... See more keywords
Silencing of microRNA‐27a facilitates autophagy and apoptosis of melanoma cells through the activation of the SYK‐dependent mTOR signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29696
Abstract: Melanoma is considered as an aggressive neoplastic transformation and featured with high metastatic potential. Although some studies have provided targets for novel therapeutic interventions, clinical development of targeted drugs for melanoma still remains obscure. Therefore,… read more here.
Keywords: melanoma; autophagy apoptosis; mir 27a; apoptosis melanoma ... See more keywords
FAM129B‐dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23295
Abstract: Incidence of melanoma continues to rise in the United States with ~100,000 new cases diagnosed in 2019. While the 5‐year survival rate of melanoma is 99% when localized, the rate of survival drops to 22.5%… read more here.
Keywords: melanoma; mutant melanoma; braf; melanoma cells ... See more keywords
Coriolus versicolor‐derived protein‐bound polysaccharides trigger the caspase‐independent cell death pathway in amelanotic but not melanotic melanoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6513
Abstract: We have investigated the potential cell death mechanism promoted by Coriolus versicolor fungus‐derived protein‐bound polysaccharides (PBPs) in melanoma cells. Knowing that melanogenesis has the potential to affect the tumor behavior and melanoma therapy outcome, the… read more here.
Keywords: melanoma; melanoma cells; coriolus versicolor; cell death ... See more keywords