Melanoma Differentiation Associated Gene-9/Syndecan Binding Protein (MDA-9/SDCBP) Promotes Hepatocellular Carcinoma (HCC).
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32797
Abstract: The oncogene Melanoma differentiation associated gene-9/syndecan binding protein (MDA-9/SDCBP) is overexpressed in many cancers promoting aggressive, metastatic disease. However, the role of MDA-9 in regulating hepatocellular carcinoma (HCC) has not been well-studied. To unravel the… read more here.
Keywords: alb mda; mda; associated gene; hcc ... See more keywords
Rapidly progressive interstitial lung disease due to anti-melanoma differentiation associated protein-5 requiring a bilateral lung transplant, and complicated by kennel cough
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2019.100886
Abstract: The association between inflammatory myopathies anti-synthetase syndrome and interstitial lung disease has been recognized since the 1950s. Patients generally present with gradual onset of symptoms and slow progression of fibrosis over months to years. Herein,… read more here.
Keywords: lung disease; interstitial lung; bilateral lung; anti melanoma ... See more keywords
Abstract 279: Lysosomal cyst(e)ine regulates melanoma de-differentiation and sensitivity to ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-279
Abstract: In response to anti-melanoma treatment, melanoma cells go through a process called de-differentiation that is characterized as loss of cellular features of melanocytes and acquisition of traits of the primitive neural crest stem cells which… read more here.
Keywords: differentiation; melanoma differentiation; sensitivity ferroptosis; sensitivity ... See more keywords
Rheumatoid Arthritis Complicated with Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Interstitial Pneumonia
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DOI: 10.2169/internalmedicine.1613-18
Abstract: Anti-melanoma differentiation-associated gene 5 (MDA5) antibodies are frequently detected in amyopathic dermatomyositis with rapidly progressive interstitial lung disease (RP-ILD). However, the presence of anti-MDA5 antibodies in other connective tissue diseases is not well known. We… read more here.
Keywords: antibody; antibody positive; rheumatoid arthritis; differentiation associated ... See more keywords
RNA-Containing Immune Complexes Formed by Anti-Melanoma Differentiation Associated Gene 5 Autoantibody Are Potent Inducers of IFN-α
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.743704
Abstract: Objective Anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody is a distinctive serology hallmark of dermatomyositis (DM). As an autoantigen, MDA5 is a cytoplasmic RNA recognition receptor. The aim of this study was to address the question… read more here.
Keywords: anti mda5; ifn; differentiation associated; anti melanoma ... See more keywords
Rare complications of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis: Time to nip them in the bud
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1009546
Abstract: Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+ DM) is an infrequent autoimmune disease, which mainly distributes in Asians and females. MDA5+ DM usually presents various skin lesions and positive anti-MDA5 antibody (a myositis-specific autoantibody for… read more here.
Keywords: rare complications; associated gene; differentiation associated; melanoma differentiation ... See more keywords
Pathogenesis of Anti-melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis: A Concise Review With an Emphasis on Type I Interferon System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.833114
Abstract: Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis (MDA5+ DM) is typically characterized by cutaneous manifestations, amyopathic or hypomyopathic muscle involvement, and a high incidence of rapid progressive interstitial lung disease (RP-ILD). However, the exact etiology and… read more here.
Keywords: melanoma differentiation; associated gene; differentiation associated; gene ... See more keywords