TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
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DOI: 10.1158/0008-5472.can-18-1214
Abstract: Although numerous epigenetic aberrancies accumulate in melanoma, their contribution to initiation and progression remain unclear. The epigenetic mark 5-hydroxymethylcytosine (5hmC), generated through TET-mediated DNA modification, is now referred to as the sixth base of DNA… read more here.
Keywords: tet2; initiation; progression; initiation progression ... See more keywords