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Anti-Tumor Effects of Engineered VNP20009-Abvec-Igκ-mPD-1 Strain in Melanoma Mice via Combining the Oncolytic Therapy and Immunotherapy

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14122789

Abstract: Programmed cell death protein 1/Programmed cell death ligand 1 (PD-1/PD-L1) immune checkpoint inhibitors are the most promising treatments for malignant tumors currently, but the low response rate limits their further clinical utilization. To address this… read more here.

Keywords: cell; melanoma mice; therapy immunotherapy; expression ... See more keywords