Cilengitide, an αvβ3-integrin inhibitor, enhances the efficacy of anti-programmed cell death-1 therapy in a murine melanoma model
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DOI: 10.1080/21655979.2022.2029236
Abstract: ABSTRACT Integrins play an important role in multiple stages of tumor progression and metastasis. Previous studies have shown synergistic effects of combined αvβ6-integrin and αvβ8-integrin inhibitors with immunotherapy. However, the role of αvβ3-integrin inhibitor in… read more here.
Keywords: cell; melanoma; therapy; melanoma model ... See more keywords
Bismuth lipophilic nanoparticles (BisBAL NP) inhibit the growth of tumor cells in a mouse melanoma model.
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DOI: 10.2174/1871520622666220215124434
Abstract: AIM The objective of this study was to analyze the antitumor effect of BisBAL NP in a mouse melanoma model. MATERIAL AND METHODS The antitumor activity of BisBAL NP on murine B16-F10 melanoma cells was… read more here.
Keywords: bisbal; mouse melanoma; melanoma model; model ... See more keywords
Human Recombinant DNase I (Pulmozyme®) Inhibits Lung Metastases in Murine Metastatic B16 Melanoma Model That Correlates with Restoration of the DNase Activity and the Decrease SINE/LINE and c-Myc Fragments in Blood Cell-Free DNA
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DOI: 10.3390/ijms222112074
Abstract: Tumor-associated cell-free DNAs (cfDNA) play an important role in the promotion of metastases. Previous studies proved the high antimetastatic potential of bovine pancreatic DNase I and identified short interspersed nuclear elements (SINEs) and long interspersed… read more here.
Keywords: dnase; lung metastases; b16 melanoma; cell free ... See more keywords
Mouse Syngeneic Melanoma Model with Human Epidermal Growth Factor Receptor Expression
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DOI: 10.3390/pharmaceutics14112448
Abstract: The development of epidermal growth factor receptor (EGFR)-targeting agents for the treatment of malignant melanoma requires cheap and easy animal tumor models for high-throughput in vivo screening. Thus, the aim of this study was to… read more here.
Keywords: melanoma; melanoma model; expression; mouse syngeneic ... See more keywords