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   Articles with "melanoma patients" as a keyword



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Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis

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recommendations! Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.2922

Abstract: BRAF and MEKis have revolutionized the management of BRAFV600‐mutated melanoma patients. Left ventricular ejection fraction decrease (LVEF‐D) related to these treatments has not been thoroughly evaluated to date. The main objective of this study was… read more here.

Keywords: melanoma; lvef; braf mekis; ventricular ejection ... See more keywords
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A systematic review with evidence mapping of supportive care interventions for melanoma patients and caregivers.

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recommendations! Published in 2023 at "Cancer medicine"

DOI: 10.1002/cam4.6012

Abstract: AIM We conducted a systematic review and evidence gap mapping to explore the existing supportive care interventions and their impact on well-being outcomes for melanoma patients and caregivers. METHODS We searched MEDLINE, Embase, Web of… read more here.

Keywords: patients caregivers; review; care interventions; melanoma patients ... See more keywords
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A model for predicting low probability of nonsentinel lymph node positivity in melanoma patients with a single positive sentinel lymph node

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recommendations! Published in 2018 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.25193

Abstract: Identifying factors associated with nonsentinel lymph node (NSN) metastases in melanoma patients with a single positive sentinel lymph node (SLN) could aid decision making regarding adjuvant therapy. We describe a model for identifying patients with… read more here.

Keywords: lymph; patients single; single positive; melanoma patients ... See more keywords
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Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers

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recommendations! Published in 2019 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.25319

Abstract: New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to… read more here.

Keywords: risk; identification risk; cutaneous melanoma; predictive markers ... See more keywords
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Completion lymphadenectomy for a positive sentinel node biopsy in melanoma patients is not associated with a survival benefit

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recommendations! Published in 2019 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.25444

Abstract: Completion lymph node dissection (CLND) for sentinel lymph node (SLN) disease in melanoma patients is debated. We evaluated the impact of CLND on survival and assessed for predictors of nonsentinel node metastasis (positive CLND). read more here.

Keywords: completion; sentinel; melanoma patients; node ... See more keywords
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S‐100B as an extra selection tool for FDG PET/CT scanning in follow‐up of AJCC stage III melanoma patients

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recommendations! Published in 2019 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.25682

Abstract: This current study assessed the value of S‐100B measurement to guide fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scanning for detecting recurrent disease in stage III melanoma patients. read more here.

Keywords: iii melanoma; melanoma patients; stage iii; pet scanning ... See more keywords
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Older melanoma patients aged 75 and above retain responsiveness to anti-PD1 therapy: results of a retrospective single-institution cohort study

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recommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-018-2219-8

Abstract: IntroductionThe utility of immunotherapy in elderly melanoma patients is debated. We aimed in this study to evaluate the efficacy and tolerability of immunotherapy among elderly patients.MethodThis is a retrospective single-institution cohort study. Patients aged 75 years… read more here.

Keywords: melanoma; institution cohort; retrospective single; study ... See more keywords
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Soluble CTLA-4 as a favorable predictive biomarker in metastatic melanoma patients treated with ipilimumab: an Italian melanoma intergroup study

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recommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-018-2258-1

Abstract: CTLA-4 blockade by means of ipilimumab (IPI) potentiates the immune response and improves overall survival (OS) in a minority of metastatic melanoma (MM) patients. We investigated the role of soluble CTLA-4 (sCTLA-4) as a possible… read more here.

Keywords: melanoma; ipi; ctla; sctla ... See more keywords
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The impact of metformin on survival in melanoma patients - National cohort study.

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recommendations! Published in 2020 at "Annals of epidemiology"

DOI: 10.1016/j.annepidem.2020.09.010

Abstract: Abstract Purpose The primary study outcome was melanoma-specific mortality in patients with type 2 diabetes mellitus (T2DM) using metformin. Methods Data regarding patients were provided by the Lithuanian Cancer Registry and were linked with National… read more here.

Keywords: melanoma; melanoma specific; metformin; melanoma patients ... See more keywords

T regulatory cells mediate immunosuppresion by adenosine in peripheral blood, sentinel lymph node and TILs from melanoma patients.

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recommendations! Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2017.12.032

Abstract: T regulatory cells (Tregs), involved in tumour tolerance, can generate Adenosine by CD39/CD73 surface enzymes, which identify four Tregs subsets: CD39+CD73- nTregs, CD39+CD73+ iTregs, CD39-CD73+ oTregs and CD39-CD73- xTregs. In melanoma patients, increased Tregs levels… read more here.

Keywords: cd39 cd73; regulatory cells; peripheral blood; melanoma patients ... See more keywords
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Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination.

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recommendations! Published in 2020 at "Cell reports"

DOI: 10.1016/j.celrep.2019.12.096

Abstract: Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are currently under evaluation for use in cancer vaccines. Although both DC subsets can activate adaptive and innate lymphocytes, their capacity to recruit such… read more here.

Keywords: human pdcs; melanoma patients; vaccination; cdc2s ... See more keywords