Contributions by MC1R Variants to Melanoma Risk in Males and Females
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.1252
Abstract: Importance Recently, the red hair variants of MC1R were found to contribute differently to pigmentation phenotype in males and females. Objective To investigate the role of these variants in melanoma risk in males and females… read more here.
Keywords: variants melanoma; risk; risk males; melanoma risk ... See more keywords
Sunscreen Use and Melanoma Risk Among Young Australian Adults
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.1774
Abstract: Importance There are limited data among young adults on sunscreen use during childhood and adulthood and on the association of sunscreen use with melanoma risk. Objective To assess correlates of early-life sunscreen use and the… read more here.
Keywords: melanoma risk; sunscreen use; use;
Citrus-Gene Interaction and Melanoma Risk in the UK Biobank.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of cancer"
DOI: 10.1002/ijc.33862
Abstract: High citrus consumption may increase melanoma risk; however, little is known about the biological mechanisms of this association, or whether it is modified by genetic variants. We conducted a genome-wide analysis of gene-citrus consumption interactions… read more here.
Keywords: melanoma risk; citrus; interaction; test ... See more keywords
Solarium Use and Risk for Malignant Melanoma: Many Open Questions, Not the Time to Close the Debate.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-46227-7_8
Abstract: To shed further light on the ongoing debate whether sunbed use may increase melanoma risk, we have critically assessed the scientific literature that is at present available, focussing on a meta-analysis that we published recently.… read more here.
Keywords: risk; use; melanoma risk; solarium use ... See more keywords
Effects of health literacy skills, educational attainment, and level of melanoma risk on responses to personalized genomic testing.
Sign Up to like & getrecommendations! Published in 2020 at "Patient education and counseling"
DOI: 10.1016/j.pec.2020.07.019
Abstract: OBJECTIVE Few studies have examined how health literacy impacts responses to genetic information. METHODS We examined this issue among 145 English or Spanish-speaking adult primary care patients enrolled in a trial that offered testing for… read more here.
Keywords: melanoma risk; health; health literacy; literacy skills ... See more keywords
Defining novel causal SNPs and linked phenotypes at melanoma-associated loci
Sign Up to like & getrecommendations! Published in 2022 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddac074
Abstract: Abstract A number of genomic regions have been associated with melanoma risk through genome-wide association studies; however, the causal variants underlying the majority of these associations remain unknown. Here, we sequenced either the full locus… read more here.
Keywords: loci; melanoma; melanoma risk; associated loci ... See more keywords
Use of antihypertensive drugs and risk of cutaneous melanoma: a nationwide nested case-control study.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of epidemiology"
DOI: 10.1093/ije/dyac223
Abstract: Abstract Background Most antihypertensives can induce dermal photosensitivity, which may increase melanoma risk. However, corroborating evidence is limited. We examined the associations between use of antihypertensives and melanoma risk. Methods A nationwide nested case-control study… read more here.
Keywords: melanoma; melanoma risk; nested case; nationwide nested ... See more keywords
Melanoma risk during immunomodulating treatment
Sign Up to like & getrecommendations! Published in 2022 at "Melanoma Research"
DOI: 10.1097/cmr.0000000000000838
Abstract: Immunosuppressive therapy is standard for the treatment of inflammatory diseases and for minimizing rejection in transplant patients. However, immunosuppressant drugs are associated with an increased risk of certain cancers. In particular, melanoma is an immunogenic… read more here.
Keywords: immunomodulating treatment; melanoma; melanoma risk; risk immunomodulating ... See more keywords
Validation of a Melanoma Risk Assessment Smartphone Application
Sign Up to like & getrecommendations! Published in 2017 at "Dermatologic Surgery"
DOI: 10.1097/dss.0000000000000916
Abstract: Given the propensity for squamous neoplasms to develop within hypertrophic LP lesions and the histological similarities between reactive and neoplastic processes in this setting, distinguishing between the 2 can represent a diagnostic challenge. Pseudoepitheliomatous hyperplasia… read more here.
Keywords: hypertrophic lesions; melanoma risk; validation melanoma; risk assessment ... See more keywords
Sensitivity of two Australian melanoma risk tools to identify high‐risk individuals among people presenting with their first primary melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.13841
Abstract: Regular skin examinations for early detection of melanoma are recommended for high‐risk individuals, but there is minimal consensus regarding what constitutes ‘high‐risk’. Melanoma risk prediction models may guide this. We compared two online melanoma risk… read more here.
Keywords: melanoma; risk tools; melanoma risk; high risk ... See more keywords
Melanoma risk alleles are associated with downregulation of the MTAP gene and hypermethylation of a CpG island upstream of the gene in dermal fibroblasts
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Dermatology"
DOI: 10.1111/exd.13247
Abstract: Several association studies and GWAS on melanoma skin cancer risk have reported statistically significant signals on 9p21.3 region, where MTAP gene maps. None of the associated SNPs identified in these studies lie in the coding… read more here.
Keywords: mtap gene; risk alleles; risk; melanoma risk ... See more keywords