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Published in 2021 at "Poultry science"
DOI: 10.1016/j.psj.2021.101567
Abstract: Melanopsin, a key light sensitive pigment, plays an important role in the regulation of bio-rhythm and photo-adaptation in poultry. This study aimed to investigate the effects of different lighting regimes on performance, pineal melanopsin expression…
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Keywords:
melanopsin;
group;
pineal melanopsin;
lighting regimes ... See more keywords
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Published in 2017 at "Gene Therapy"
DOI: 10.1038/gt.2017.63
Abstract: Several preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of long-term expression of these optogenes…
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Keywords:
melanopsin;
long term;
channelrhodopsin;
term expression ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13939-3
Abstract: Melanopsin (OPN4) is a photo-pigment found in a small subset of intrinsically photosensitive ganglion cells (ipRGCs) of the mammalian retina. These cells play a role in synchronizing the central circadian pacemaker to the astronomical day…
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Keywords:
melanopsin;
canonical light;
melanopsin canonical;
heat ... See more keywords
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Published in 2018 at "Neuro-Ophthalmology"
DOI: 10.1080/01658107.2017.1344251
Abstract: ABSTRACT Previously, it has been reported that melanopsin-mediated pupillary light response (PLR), measured with pupillometry, is reduced in patients with idiopathic intracranial hypertension (IIH), indicating the clinical utility of the tool in the diagnosis of…
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Keywords:
melanopsin;
pupillary light;
melanopsin mediated;
idiopathic intracranial ... See more keywords
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Published in 2023 at "Science"
DOI: 10.1126/science.ade2024
Abstract: Light regulates physiology, mood, and behavior through signals sent to the brain by intrinsically photosensitive retinal ganglion cells (ipRGCs). How primate ipRGCs sense light is unclear, as they are rare and challenging to target for…
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Keywords:
primate;
melanopsin;
environmental illumination;
encoding environmental ... See more keywords
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Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285053
Abstract: Melanopsin reportedly contributes to brightness and color appearance in photopic vision in addition to cone photoreceptor cells. However, the relationship between the contribution of melanopsin to color appearance and retinal location is unclear. Herein, we…
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Keywords:
melanopsin stimulation;
high melanopsin;
color appearance;
melanopsin ... See more keywords
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Published in 2022 at "EMBO Reports"
DOI: 10.15252/embr.202051528
Abstract: Mammalian and fish pineals play a key role in adapting behaviour to the ambient light conditions through the release of melatonin. In mice, light inhibits nocturnal locomotor activity via the nonāvisual photoreceptor Melanopsin. In contrast…
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Keywords:
locomotor activity;
diurnal zebrafish;
melanopsin;
activity ... See more keywords
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Published in 2020 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-202178
Abstract: BACKGROUND Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) signal the environmental light to mediate circadian photoentrainment and sleep-wake cycles. There is high prevalence of circadian and sleep disruption in people with Parkinson's disease; however, the…
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Keywords:
parkinson disease;
sleep disruption;
disease;
melanopsin ... See more keywords
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Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1090037
Abstract: Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, imparting to themselves the ability to respond to light in the absence of input from rod or cone photoreceptors. Since their discovery ipRGCs have been…
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Keywords:
knockout;
melanopsin;
rod cone;
evoked potentials ... See more keywords
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Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1114634
Abstract: Introduction: Intrinsically photosensitive retinal ganglion cells (ipRGCs) integrate melanopsin and rod/cone-mediated inputs to signal to the brain. Whilst originally identified as a cell type specialised for encoding ambient illumination, several lines of evidence indicate a…
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Keywords:
cone;
cone mediated;
retina;
mediated responses ... See more keywords
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Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1132230
Abstract: Traditional photoreceptors utilize the chromophore retinal to absorb light coupled with a unique opsin protein to specify receptor spectral sensitivity. Light absorption triggers a cascade of events transducing light energy to neural signals beginning with…
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Keywords:
ganglion;
melanopsin;
ganglion cells;
visual threshold ... See more keywords