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Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22010141
Abstract: This article reviews the dynamic interactions of the tumour microenvironment, highlighting the roles of acetyl-CoA and melatonergic pathway regulation in determining the interactions between oxidative phosphorylation (OXPHOS) and glycolysis across the array of cells forming…
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Keywords:
microenvironment;
acetyl coa;
metabolic interactions;
melatonergic pathway ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010311
Abstract: There is a growing interest in the role of alterations in mitochondrial metabolism in the pathoetiology and pathophysiology of cancers, including within the array of diverse cells that can form a given tumor microenvironment. The…
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Keywords:
intercellular interactions;
role;
tumor microenvironment;
mitochondrial melatonergic ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010350
Abstract: Major depressive disorder (MDD) is widely accepted as having a heterogenous pathophysiology involving a complex mixture of systemic and CNS processes. A developmental etiology coupled to genetic and epigenetic risk factors as well as lifestyle…
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Keywords:
melatonergic pathway;
depression pathophysiology;
mitochondrial melatonergic;
astrocyte mitochondrial ... See more keywords