Articles with "melatonergic pathway" as a keyword



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Tumour Microenvironment: Roles of the Aryl Hydrocarbon Receptor, O-GlcNAcylation, Acetyl-CoA and Melatonergic Pathway in Regulating Dynamic Metabolic Interactions across Cell Types—Tumour Microenvironment and Metabolism

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22010141

Abstract: This article reviews the dynamic interactions of the tumour microenvironment, highlighting the roles of acetyl-CoA and melatonergic pathway regulation in determining the interactions between oxidative phosphorylation (OXPHOS) and glycolysis across the array of cells forming… read more here.

Keywords: microenvironment; acetyl coa; metabolic interactions; melatonergic pathway ... See more keywords
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Tumor Microenvironment and Metabolism: Role of the Mitochondrial Melatonergic Pathway in Determining Intercellular Interactions in a New Dynamic Homeostasis

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24010311

Abstract: There is a growing interest in the role of alterations in mitochondrial metabolism in the pathoetiology and pathophysiology of cancers, including within the array of diverse cells that can form a given tumor microenvironment. The… read more here.

Keywords: intercellular interactions; role; tumor microenvironment; mitochondrial melatonergic ... See more keywords
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Depression Pathophysiology: Astrocyte Mitochondrial Melatonergic Pathway as Crucial Hub

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24010350

Abstract: Major depressive disorder (MDD) is widely accepted as having a heterogenous pathophysiology involving a complex mixture of systemic and CNS processes. A developmental etiology coupled to genetic and epigenetic risk factors as well as lifestyle… read more here.

Keywords: melatonergic pathway; depression pathophysiology; mitochondrial melatonergic; astrocyte mitochondrial ... See more keywords