Inhibiting MT2‐TFE3‐dependent autophagy enhances melatonin‐induced apoptosis in tongue squamous cell carcinoma
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DOI: 10.1111/jpi.12457
Abstract: Autophagy modulation is a potential therapeutic strategy for tongue squamous cell carcinoma (TSCC). Melatonin possesses significant anticarcinogenic activity. However, whether melatonin induces autophagy and its roles in cell death in TSCC are unclear. Herein, we… read more here.
Keywords: dependent autophagy; melatonin induced; melatonin; cell ... See more keywords
Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells
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DOI: 10.1186/s12868-019-0545-1
Abstract: BackgroundAutophagy is considered to be another restorative focus for the treatment of brain tumors. Although several research have demonstrated that melatonin induces autophagy in colon cancer and hepatoma cells, there has not been any direct… read more here.
Keywords: glioblastoma; apoptosis; melatonin induced; autophagy triggers ... See more keywords
Periostin has a protective role in melatonin‑induced cell apoptosis by inhibiting the eIF2α‑ATF4 pathway in human osteoblasts.
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DOI: 10.3892/ijmm.2017.3300
Abstract: The present study aimed to investigate the role of periostin (POSTN) and high melatonin concentrations in the apoptosis of hFOB 1.19 human normal fetal osteoblastic cells. hFOB 1.19 human osteoblastic cells were stably cultured and treated… read more here.
Keywords: eif2 atf4; apoptosis; melatonin induced; atf4 pathway ... See more keywords