Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K‐AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Birth Defects Research"
DOI: 10.1002/bdr2.1938
Abstract: Our recent epidemiological study revealed that maternal sleep during the periconceptional period should be involved in the risk of congenital heart disease (CHD) in offspring. Melatonin, a sleep related hormone, has been suggested to play… read more here.
Keywords: cell; embryonic rat; melatonin inhibits; inhibits embryonic ... See more keywords
Melatonin Inhibits Ethylene Synthesis via Nitric Oxide Regulation To Delay Postharvest Senescence in Pears.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b06580
Abstract: Understanding ripening and senescence processes in postharvest stored fruit is key to the identification and implementation of effective treatment methods. Here, we explored the effects of exogenous applications of melatonin (MT) and nitric oxide (NO)… read more here.
Keywords: ethylene synthesis; senescence; melatonin inhibits; inhibits ethylene ... See more keywords
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cell Cycle"
DOI: 10.1080/15384101.2020.1810401
Abstract: ABSTRACT Background: Deposition of various crystal and organic substances in the kidney can lead to kidney stone formation. Melatonin is an effective endogenous antioxidant that can prevent crystalluria and kidney damage due to crystal formation… read more here.
Keywords: stress apoptosis; melatonin inhibits; endoplasmic reticulum; apoptosis ... See more keywords
Melatonin inhibits endometriosis development by disrupting mitochondrial function and regulating tiRNAs
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12842
Abstract: Endometriosis is a benign gynecological disease characterized by abnormal growth of endometrial‐like cells outside the uterus. Melatonin, a hormone secreted by the pineal gland, has been shown to have therapeutic effects in various diseases, including… read more here.
Keywords: endometriosis; stromal cells; inhibits endometriosis; endometriosis development ... See more keywords
Melatonin inhibits the inflammation and apoptosis in rats with diabetic retinopathy via MAPK pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202007_22183
Abstract: The article "Melatonin inhibits the inflammation and apoptosis in rats with diabetic retinopathy via MAPK pathway, by Y. Ma, Q. Zhao, Y. Shao, M.-Z. Cao, M. Zhao, D. Wang, published in Eur Rev Med Pharmacol… read more here.
Keywords: inhibits inflammation; rats diabetic; diabetic retinopathy; apoptosis rats ... See more keywords
Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.885293
Abstract: Calcific aortic valve disease (CAVD) is linked to high mortality. Melatonin inhibits nuclear factor-kappa B (NF-κB)/cyclic AMP response element-binding protein (CREB), contributing to CAVD progression. This study determined the role of melatonin/MT1/MT2 signaling in valvular… read more here.
Keywords: aortic valve; calcification; creb runx2; melatonin inhibits ... See more keywords