Melatonin loaded PLGA nanoparticles effectively ameliorate the in vitro maturation of deteriorated oocytes and the cryoprotective abilities during vitrification process.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm02054h
Abstract: Almost all cells can be exposed to stress, but oocytes, which are female germ cells, are particularly vulnerable to damage. In this study, melatonin, a well-known antioxidant, was loaded into biodegradable poly(lactic-co-glycolic acid) (PLGA) nanoparticles… read more here.
Keywords: cryoprotective abilities; deteriorated oocytes; melatonin loaded; plga nanoparticles ... See more keywords
Regeneration of Critical-Sized Grade II Furcation Using a Novel Injectable Melatonin-Loaded Scaffold.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14314
Abstract: BACKGROUND Periodontal regenerative therapy using bone-substituting materials has gained favorable clinical significance in enhancing osseous regeneration. These materials should be biocompatible, osteogenic, malleable, and biodegradable. This study assessed the periodontal regenerative capacity of a novel… read more here.
Keywords: regeneration; melatonin loaded; bone; critical sized ... See more keywords
Topical Administration of Melatonin-Loaded Extracellular Vesicle-Mimetic Nanovesicles Improves 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis
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DOI: 10.3390/biom11101450
Abstract: Atopic dermatitis (AD) is caused by multiple factors that trigger chronic skin inflammation, including a defective skin barrier, immune cell activation, and microbial exposure. Although melatonin has an excellent biosafety profile and a potential to… read more here.
Keywords: transdermal delivery; melatonin loaded; melanvs; delivery ... See more keywords
Preparation of Melatonin-Loaded Nanoparticles with Targeting and Sustained Release Function and Their Application in Osteoarthritis
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DOI: 10.3390/ijms24108740
Abstract: (1) The vicious cycle of innate immune response and reactive oxygen species (ROS) generation is an important pathological process of osteoarthritis (OA). Melatonin may be a new hope for the treatment of OA because of… read more here.
Keywords: melatonin loaded; cartilage; osteoarthritis; plga ... See more keywords
Melatonin-Loaded Nanocarriers: New Horizons for Therapeutic Applications
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DOI: 10.3390/molecules26123562
Abstract: The use of nanosized particles has emerged to facilitate selective applications in medicine. Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine-tuned therapy, enhancing the therapeutic efficacy of chemical agents at the molecular… read more here.
Keywords: new horizons; melatonin loaded; horizons therapeutic; nanocarriers new ... See more keywords