Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling.
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DOI: 10.3892/or.2018.6339
Abstract: Retinoblastoma (Rb) is the most frequent primary intraocular tumor usually diagnosed in infants and children, and current therapy for such disease is still limited. Corosolic acid (CA), an ursane-type pentacyclic triterpene, has been assessed as a promising… read more here.
Keywords: cell cycle; retinoblastoma; melk foxm1; human retinoblastoma ... See more keywords