MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
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DOI: 10.3892/or.2019.6988
Abstract: Maternal embryonic leucine zipper kinase (MELK) has been reported to serve critical roles in the maintenance of stemness of cancer cells, although its mechanism remains unclear. Since SRY‑box 2 (SOX2) was demonstrated to be involved… read more here.
Keywords: cancer; sox2 expression; melk inhibition; sox2 ... See more keywords