Supplemental hot melt extruded nano-selenium increases expression profiles of antioxidant enzymes in the livers and spleens of weanling pigs
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DOI: 10.1016/j.anifeedsci.2019.114381
Abstract: Abstract A study was conducted to determine the effect of dietary selenium (Se) concentration and source for weanling pigs on serum Se, glutathione peroxidase (GPx) activity and performance. A total of 120 weanling pigs with… read more here.
Keywords: supplemental hot; weanling pigs; hot melt; selenium ... See more keywords
A Rational Design of a Biphasic Dissolution Setup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion
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DOI: 10.3390/pharmaceutics12030237
Abstract: Biphasic dissolution systems achieved good predictability for the in vivo performance of several formulations of poorly water-soluble drugs by characterizing dissolution, precipitation, re-dissolution, and absorption. To achieve a high degree of predictive performance, acceptor media,… read more here.
Keywords: solid dispersion; amorphous solid; hot melt; biphasic dissolution ... See more keywords
Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation
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DOI: 10.3390/pharmaceutics12080757
Abstract: The aim of this study was to control the dissolution rate and permeability of cilostazol. To enhance the dissolution rate of the active pharmaceutical ingredient (API), hot-melt extrusion (HME) technology was applied to prepare a… read more here.
Keywords: absorption; preparation hot; hot melt; simulation ... See more keywords