Nickel-Catalyzed Annulation of Aliphatic Amides with AlkynylÂsilanes: An Expeditious Approach to Five-Membered Lactams
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DOI: 10.1055/s-0037-1610756
Abstract: An expeditious approach for the synthesis of diverse five-membered lactams through nickel-catalyzed annulation of the C(sp3)–H bonds of aliphatic amides with alkynylsilanes assisted by an 8-aminoquinolinyl directing group is reported, delivering the corresponding lactam derivatives… read more here.
Keywords: five membered; expeditious approach; aliphatic amides; membered lactams ... See more keywords