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   Articles with "membrane" as a keyword



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Recent advances in nanodisc technology for membrane protein studies (2012–2017)

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recommendations! Published in 2017 at "FEBS Letters"

DOI: 10.1002/1873-3468.12706

Abstract: Historically, the main barrier to membrane protein investigations has been the tendency of membrane proteins to aggregate (due to their hydrophobic nature), in aqueous solution as well as on surfaces. The introduction of biomembrane mimetics… read more here.

Keywords: membrane proteins; microscopy; membrane protein; recent advances ... See more keywords

The peroxisome biogenesis factors Pex3 and Pex19: multitasking proteins with disputed functions

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recommendations! Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13340

Abstract: The peroxisomal membrane protein (PMP) Pex3 and its cytosolic interaction partner Pex19 have been implicated in peroxisomal membrane biogenesis. Although these peroxins have been extensively studied, no consensus has been reached yet on how they… read more here.

Keywords: biogenesis factors; peroxisomal membrane; pex3 pex19; peroxisome biogenesis ... See more keywords

Sticholysin I–II oligomerization in the absence of membranes

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14326

Abstract: Sticholysins are pore‐forming toxins produced by the sea anemone Stichodactyla helianthus. When they encounter a sphingomyelin‐containing membrane, these proteins bind to it and oligomerize, a process that ends in pore formation. Mounting evidence indicates that StnII… read more here.

Keywords: oligomerization; oligomerization absence; absence membranes; membrane ... See more keywords

On the role of ubiquinone in the proton translocation mechanism of respiratory complex I

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14506

Abstract: Complex I converts oxidoreduction energy into a proton electrochemical gradient across the inner mitochondrial or bacterial cell membrane. This gradient is the primary source of energy for aerobic synthesis of ATP. Oxidation of reduced nicotinamide… read more here.

Keywords: proton translocation; translocation; role ubiquinone; membrane ... See more keywords

Vacuole membrane contact sites regulate liquid-ordered domain formation during glucose starvation.

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recommendations! Published in 2023 at "FEBS letters"

DOI: 10.1002/1873-3468.14621

Abstract: Liquid-ordered (Lo) membrane domains have been proposed to play important roles in a wide variety of biological processes, such as protein sorting and cell signaling. However, the mechanisms by which they are formed and maintained… read more here.

Keywords: glucose starvation; contact sites; membrane contact; domain formation ... See more keywords

Unraveling membrane protein localization and interactions in nanodiscs

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recommendations! Published in 2024 at "FEBS Letters"

DOI: 10.1002/1873-3468.15059

Abstract: Nanodiscs, consisting of a lipid bilayer surrounded by membrane scaffold proteins (MSPs), are extensively used to study membrane proteins (MPs) because they provide a stable lipid environment. However, the precise mechanism governing MP behavior within… read more here.

Keywords: protein localization; interactions nanodiscs; unraveling membrane; membrane ... See more keywords

Suppressed de novo lipogenesis by plasma membrane citrate transporter inhibitor promotes apoptosis in HepG2 cells

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recommendations! Published in 2018 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12435

Abstract: Suppression of the expression or activities of enzymes that are involved in the synthesis of de novo lipogenesis (DNL) in cancer cells triggers cell death via apoptosis. The plasma membrane citrate transporter (PMCT) is the… read more here.

Keywords: citrate; apoptosis; hepg2 cells; pmcti ... See more keywords
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Glycosphingolipids within membrane contact sites influence their function as signaling hubs in neurodegenerative diseases.

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recommendations! Published in 2023 at "FEBS open bio"

DOI: 10.1002/2211-5463.13605

Abstract: Intracellular organelles carry out many of their functions by engaging in extensive inter-organellar communication through specialized membrane contact sites (MCSs) formed where two organelles tether to each other or to the plasma membrane without fusing.… read more here.

Keywords: contact sites; membrane contact; signaling hubs; membrane ... See more keywords

Protein insertion into the inner membrane of mitochondria: routes and mechanisms

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recommendations! Published in 2024 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13806

Abstract: The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation… read more here.

Keywords: inner membrane; insertion; membrane; membrane proteins ... See more keywords

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

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recommendations! Published in 2025 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13966

Abstract: Neurotransmitter release is triggered in microseconds by the two C2 domains of the Ca2+ sensor synaptotagmin‐1 and by SNARE complexes, which form four‐helix bundles that bridge the vesicle and plasma membranes. The synaptotagmin‐1 C2B domain… read more here.

Keywords: fusion; dynamics simulations; molecular dynamics; synaptotagmin ... See more keywords
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Trypsin‐Free Cultivation of 3D Mini‐Tissues in an Adaptive Membrane Bioreactor

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recommendations! Published in 2020 at "Advanced Biosystems"

DOI: 10.1002/adbi.202000081

Abstract: The production of large scaffold‐free tissues is a key challenge in regenerative medicine. Nowadays, temperature‐responsive polymers allow intact tissue harvesting without needing proteolytic enzymes. This method is limited to tissue culture plastic with limited upscaling… read more here.

Keywords: medicine; cultivation; membrane bioreactor; trypsin free ... See more keywords