Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle‐based vaccine platform, for efficient viral antigen delivery
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12247
Abstract: Abstract Vaccine platforms enable fast development, testing, and manufacture of more affordable vaccines. Here, we evaluated Generalized Modules for Membrane Antigens (GMMA), outer membrane vesicles (OMVs) generated by genetically modified Gram‐negative bacteria, as a vaccine… read more here.
Keywords: vaccine platform; platform; generalized modules; membrane antigens ... See more keywords
Chemotherapy and Physical Therapeutics Modulate Antigens on Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.889950
Abstract: Cancer cells possess specific properties, such as multidrug resistance or unlimited proliferation potential, due to the presence of specific proteins on their cell membranes. The release of proliferation-related proteins from the membrane can evoke a… read more here.
Keywords: anticancer therapy; cancer cells; cancer; membrane antigens ... See more keywords
Effect of O-Antigen Chain Length Regulation on the Immunogenicity of Shigella and Salmonella Generalized Modules for Membrane Antigens (GMMA)
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DOI: 10.3390/ijms22031309
Abstract: Recently, generalized modules for membrane antigens (GMMA) technology has been proposed as an alternative approach to traditional glycoconjugate vaccines for O-antigen delivery. Saccharide length is a well-known parameter that can impact the immune response induced… read more here.
Keywords: length; antigens gmma; modules membrane; generalized modules ... See more keywords
Molecular Signature of Monocytes Shaped by the Shigella sonnei 1790-Generalized Modules for Membrane Antigens Vaccine
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25021116
Abstract: Shigellosis, an acute gastroenteritis infection caused by Shigella species, remains a public health burden in developing countries. Recently, many outbreaks due to Shigella sonnei multidrug-resistant strains have been reported in high-income countries, and the lack… read more here.
Keywords: shigella sonnei; sonnei 1790; membrane antigens; generalized modules ... See more keywords