Modeling Membrane Associated Proteins through Neutron Reflectivity Augmented Molecular Dynamics
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.770
Abstract: The structural characterization of membrane-associated proteins on fluid lipid bilayers remains a challenge to most modern biophysical techniques. Neutron reflectivity (NR) has emerged as a method that provides sub-nanometer resolution of proteins in a functional… read more here.
Keywords: protein; associated proteins; density; neutron reflectivity ... See more keywords
Bisphenol A induces human uterine leiomyoma cell proliferation through membrane-associated ERα36 via nongenomic signaling pathways
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.01.001
Abstract: The role of ERα36 in regulating BPA's effects and its potential as a risk factor for human uterine fibroids were evaluated. BPA at low concentrations (10-6 μM - 10 μM) increased proliferation by facilitating progression of hormonally… read more here.
Keywords: nongenomic signaling; signaling pathways; proliferation; membrane associated ... See more keywords
Functional expression and purification of CYP93C20, a plant membrane-associated cytochrome P450 from Medicago truncatula.
Sign Up to like & getrecommendations! Published in 2018 at "Protein expression and purification"
DOI: 10.1016/j.pep.2018.04.017
Abstract: Plants possess very large numbers of biosynthetic cytochrome P450 enzymes. In spite of the importance of these enzymes for the synthesis of bioactive plant secondary metabolites, only two plant P450 structures has been obtained to… read more here.
Keywords: plant; expression; membrane associated; cytochrome p450 ... See more keywords
Membrane-Associated RNA-Binding Proteins Orchestrate Organelle-Coupled Translation.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2018.10.005
Abstract: Proteins are positioned and act at defined subcellular locations. This is particularly important in eukaryotic cells that deliver proteins to membrane-bound organelles such as the endoplasmic reticulum (ER), mitochondria, or endosomes. It is axiomatic that… read more here.
Keywords: binding proteins; rna binding; translation; membrane associated ... See more keywords
The expression and purification of DGD2 - a chloroplast outer membrane associated glycosyltransferase for galactolipid synthesis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00028
Abstract: Galactolipids are characteristic lipids of the photosynthetic membranes. They are highly enriched in the chloroplast and are present in photosystem structures. There are two major types of galactolipids, i.e., monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) in… read more here.
Keywords: dgd2; expression; membrane associated; purification ... See more keywords
Purification and Characterization of a Stable, Membrane-Associated Peptidoglycan Responsive Adenylate Cyclase LRR Domain from Human Commensal Candida albicans.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00305
Abstract: The evolutionarily conserved leucine rich repeat (LRR) protein domain is a unique structural motif found in many viral, bacterial, archaeal, and eukaryotic proteins. The LRR domain serves many roles, including being a signaling domain and… read more here.
Keywords: domain; lrr domain; candida albicans; membrane associated ... See more keywords
Reconstitution of the Linaridin Pathway Provides Access to the Family-Determining Activity of Two Membrane-Associated Proteins in the Formation of Structurally Underestimated Cypemycin.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c01730
Abstract: Cypemycin is a parent linaridin peptide known to contain nonproteinogenic dehydrobutyrine, N,N-dimethylalanine, and aminovinyl-cysteine residues. The enzymatic process by which this ribosomally synthesized peptide is formed remains elusive largely because of the deficiency of knowledge… read more here.
Keywords: membrane associated; two membrane; family determining; activity ... See more keywords
Nε-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function
Sign Up to like & getrecommendations! Published in 2018 at "Nature Microbiology"
DOI: 10.1038/s41564-018-0215-6
Abstract: Shigella flexneri, an intracellular Gram-negative bacterium causative for shigellosis, employs a type III secretion system to deliver virulence effectors into host cells. One such effector, IcsB, is critical for S. flexneri intracellular survival and pathogenesis,… read more here.
Keywords: fatty acylation; associated proteins; acylation; host ... See more keywords
Strategies for picking membrane-associated particles within subtomogram averaging workflows
Sign Up to like & getrecommendations! Published in 2022 at "Faraday Discussions"
DOI: 10.1039/d2fd00022a
Abstract: Cryo-electron tomography (cryo-ET) with subtomogram averaging (STA) has emerged as a key tool for determining macromolecular structure(s) in vitro and in situ. However, processing cryo-ET data with STA currently requires significant user expertise. Recent efforts… read more here.
Keywords: membrane associated; subtomogram averaging; associated particles; strategies picking ... See more keywords
Chemokine (C-C motif) ligand 18/membrane-associated 3/forkhead box O1 axis promotes the proliferation, migration, and invasion of intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2069383
Abstract: ABSTRACT Phosphatidylinositol Transfer Protein, Membrane-Associated 3 (PITPNM3) often bind with chemokine (C-C motif) ligand 18 (CCL18) to promote tumor progression. However, the role of PITPNM3 in intrahepatic cholangiocarcinoma (ICC) is unclear. We first searched GEPIA… read more here.
Keywords: cell; migration invasion; proliferation migration; membrane associated ... See more keywords
Expression of inhibitory receptors by B cells in chronic human infectious diseases restricts responses to membrane-associated antigens
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aba6493
Abstract: Atypical memory B cell antigens must be membrane associated to force exclusion of inhibitory receptors from the immune synapse. Chronic human infectious diseases, including malaria, are associated with a large expansion of a phenotypically and… read more here.
Keywords: responses membrane; infectious diseases; chronic human; human infectious ... See more keywords