Insilico prediction and pharmacokinetic studies on glucosinolates as potential drug and key inhibitor molecule for lanosterol-14α-demethylase, fungal membrane biosynthesis.
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DOI: 10.2174/1570163819666220615142933
Abstract: BACKGROUND Glucosinolates (b-thioglucoside-N-hydroxysulfates) are a water-soluble organic anion with sulfur- and nitrogen-containing glycosides which are found in abundance in Cruciferous plants. Ergosterol (ERG13) lanosterol-14α-demethylase protein has been targeted for inihibition studies as a key regulator… read more here.
Keywords: demethylase; lanosterol demethylase; membrane biosynthesis; fungal membrane ... See more keywords