Plasma membrane Ca2+-permeable channels and sodium/calcium exchangers in tumorigenesis and tumor development of the upper gastrointestinal tract.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.01.026
Abstract: The upper gastrointestinal (GI) tumors are multifactorial diseases associated with a combination of oncogenes and environmental factors. Currently, surgery, chemotherapy, radiotherapy and immunotherapy are relatively effective treatment options for the patients with these tumors. However,… read more here.
Keywords: permeable channels; channels sodium; plasma membrane; ca2 ... See more keywords
Functional interplay between plasma membrane Ca2+-ATPase, amyloid β-peptide and tau
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DOI: 10.1016/j.neulet.2017.08.004
Abstract: It is well known that dysregulation of Ca2+ homeostasis is involved in Alzheimeŕs disease (AD), a neurodegenerative disorder characterized by the presence of toxic aggregates of amyloid β-peptide (Aβ) and neurofibrillary tangles of tau. Alteration… read more here.
Keywords: amyloid peptide; ca2 atpase; ca2; membrane ca2 ... See more keywords
Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance
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DOI: 10.1016/j.neuron.2017.09.038
Abstract: Plasma membrane Ca2+-ATPases (PMCAs), a family of P-type ATPases, extrude Ca2+ ions from the cytosol to the extracellular space and are considered to be key regulators of Ca2+ signaling. Here we show by functional proteomics… read more here.
Keywords: key regulators; neuroplastin basigin; ca2; membrane ca2 ... See more keywords
Ca2+ Homeostasis by Plasma Membrane Ca2+ ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021442
Abstract: The strength of Ca2+ signaling is a hallmark of T cell activation, yet the role of Ca2+ homeostasis in developing T cells before expressing a mature T cell receptor is poorly understood. We aimed to… read more here.
Keywords: ca2 homeostasis; development; membrane ca2; ca2 ... See more keywords