Enhanced stability designs of cell membrane chromatography for screening drug leads.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200200
Abstract: Cell membrane chromatography is an effective method for screening bioactive components acting on specific receptors in complex systems, which maintains the biological activity of the membrane receptors and improves screening efficiency. However, traditional cell membrane… read more here.
Keywords: membrane chromatography; cell membrane; stability; membrane ... See more keywords
Evaluation of two-species binding model with anion-exchange membrane chromatography to predict pressure buildup during recovery of virus
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2021.116535
Abstract: Abstract Membrane chromatography is an emerging bioprocessing technology. This work aimed to determine the cause of pressure rise during the loading phase of a large-scale viral recovery process, through small-scale experimentation. Comparable pressure rise was… read more here.
Keywords: membrane chromatography; anion exchange; pressure; pressure rise ... See more keywords
Platform approach for the AAV purification process including membrane chromatography for polishing
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.393
Abstract: Background & Aim The approval of gene therapies delivered by Adeno-Associated Viruses (AAVs) has resulted in an increased commitment to adopt AAV as the vector of choice to address a broad range of diseases. The… read more here.
Keywords: chromatography; membrane chromatography; step; platform ... See more keywords
Use of the Dispersion Coefficient as the Sole Structural Parameter to Model Membrane Chromatography
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12070668
Abstract: The characterization and modelling of membrane chromatography processes require the axial dispersion coefficient as a relevant and effective intrinsic property of porous media, instead of arbitrary assumptions on pore size distribution. The dispersion coefficient can… read more here.
Keywords: dispersion; model; dispersion coefficient; membrane chromatography ... See more keywords
Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10081310
Abstract: New influenza strains are constantly emerging, causing seasonal epidemics and raising concerns to the risk of a new global pandemic. Since vaccination is an effective method to prevent the spread of the disease and reduce… read more here.
Keywords: cell culture; membrane chromatography; influenza vaccines; downstream ... See more keywords