Cisplatin‐induced alteration on membrane composition of A549 cells revealed by ToF‐SIMS
Sign Up to like & getrecommendations! Published in 2019 at "Surface and Interface Analysis"
DOI: 10.1002/sia.6714
Abstract: Cisplatin has been clinically used for treatment of solid tumors such as non–small‐cell lung cancer for decades. However, tumor resistance may be acquired with losing the antitumor activity of cisplatin. As cellular membrane is the… read more here.
Keywords: a549 ddp; tof sims; membrane; membrane composition ... See more keywords
KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14177
Abstract: Ciliary membrane composition is controlled by transition zone (TZ) proteins such as RPGRIP1, RPGRIPL and NPHP4, which are vital for balanced coordination of diverse signalling systems like the Sonic hedgehog (Shh) pathway. Activation of this… read more here.
Keywords: sonic hedgehog; membrane composition; transition zone;
Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21041317
Abstract: Doxorubicin (DXR) is a drug widely used in chemotherapy. Its mode of action is based on its intercalation properties, involving the inhibition of topoisomerase II. However, few studies have reported the mitochondrial effects of DXR… read more here.
Keywords: phosphatidylserine decarboxylase; mitochondrial membrane; membrane; membrane composition ... See more keywords