An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.07.021
Abstract: Summary The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane fission from within membrane necks, a process that is essential for many cellular functions, from cell division to lysosome degradation and autophagy. How it… read more here.
Keywords: escrt iii; fission; deformation fission; membrane deformation ... See more keywords
Label-Free Quantification of Small-Molecule Binding to Membrane Proteins on Single Cells by Tracking Nanometer-Scale Cellular Membrane Deformation.
Sign Up to like & getrecommendations! Published in 2018 at "ACS nano"
DOI: 10.1021/acsnano.8b00235
Abstract: Measuring molecular binding to membrane proteins is critical for understanding cellular functions, validating biomarkers, and screening drugs. Despite the importance, developing such a capability has been a difficult challenge, especially for small-molecule binding to membrane… read more here.
Keywords: membrane proteins; binding membrane; single cells; membrane ... See more keywords
Membrane deformation and layer-by-layer peeling of giant vesicles induced by the pore-forming toxin pneumolysin.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00134d
Abstract: Protein-membrane interactions that modify the shape of membranes are important for generating curvature, membrane deformation by protein-protein crowding or trafficking of vesicles. Giant vesicles represent a simplified but versatile model for biological membranes and are… read more here.
Keywords: membrane deformation; layer; giant vesicles; microscopy ... See more keywords
Macrophages modulate stiffness-related foreign body responses through plasma membrane deformation.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2213837120
Abstract: Implants are widely used in medical applications and yet macrophage-mediated foreign body reactions caused by implants severely impact their therapeutic effects. Although the extensive use of multiple surface modifications has been introduced to provide some… read more here.
Keywords: membrane deformation; stiffness; foreign body;
Recruitment of Irgb6 to the membrane is a direct trigger for membrane deformation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.992198
Abstract: Irgb6 is a member of interferon γ-induced immunity related GTPase (IRG), and one of twenty “effector” IRGs, which coordinately attack parasitophorous vacuole membrane (PVM), causing death of intracellular pathogen. Although Irgb6 plays a pivotal role… read more here.
Keywords: membrane deformation; irgb6 membrane; gtpase; membrane ... See more keywords