A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14951-4
Abstract: Gram-negative bacteria deliver effectors via the type VI secretion system (T6SS) to outcompete their rivals. Each bacterial strain carries a different arsenal of effectors; the identities of many remain unknown. Here, we present an approach… read more here.
Keywords: comparative genomics; methodology; t6ss effectors; family ... See more keywords
Nano-viscosimetry analysis of the membrane disrupting action of the bee venom peptide melittin
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47325-y
Abstract: Melittin is one of the most studied α-helical cationic membrane disrupting peptides. It is the main component of bee venom, however it is considered an antimicrobial peptide for its ability to kill bacteria. Melittin is… read more here.
Keywords: bee venom; melittin; membrane disrupting; disrupting action ... See more keywords
An active machine learning discovery platform for membrane-disrupting and pore-forming peptides
Sign Up to like & getrecommendations! Published in 2024 at "Physical Chemistry Chemical Physics"
DOI: 10.1039/d4cp01404a
Abstract: Membrane-disrupting and pore-forming peptides (PFPs) play a substantial role in bionanotechnology and can determine the life and death of cells. The control of chemical and ion transport through cell membranes is essential to maintaining concentration… read more here.
Keywords: membrane disrupting; pore forming; disrupting pore; forming peptides ... See more keywords