The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0191882
Abstract: Despite decades of research, the mechanism of action of the ABC multidrug transporter P-glycoprotein (P-gp) remains elusive. Due to experimental limitations, many researchers have turned to molecular dynamics simulation studies in order to investigate different… read more here.
Keywords: multidrug transporter; membrane environment; molecular dynamics; transporter glycoprotein ... See more keywords
Detergent-Free Isolation of Membrane Proteins and Strategies to Study Them in a Near-Native Membrane Environment
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081076
Abstract: Atomic-resolution structural studies of membrane-associated proteins and peptides in a membrane environment are important to fully understand their biological function and the roles played by them in the pathology of many diseases. However, the complexity… read more here.
Keywords: membrane environment; membrane proteins; membrane; free isolation ... See more keywords