Calorimetry Methods to Study Membrane Interactions and Perturbations Induced by Antimicrobial Host Defense Peptides.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6737-7_9
Abstract: Biological membranes play an important role in determining the activity and selectivity of antimicrobial host defense peptides (AMPs). Several biophysical methods have been developed to study the interactions of AMPs with biological membranes. Isothermal titration… read more here.
Keywords: methods study; defense peptides; host defense; membrane interactions ... See more keywords
Comparing activity, toxicity and model membrane interactions of Jelleine-I and Trp/Arg analogs: analysis of peptide aggregation
Sign Up to like & getrecommendations! Published in 2020 at "Amino Acids"
DOI: 10.1007/s00726-020-02847-y
Abstract: Increasing resistance in antibiotic and chemotherapeutic treatments has been pushing studies of design and evaluation of bioactive peptides. Designing relies on different approaches from minimalist sequences and endogenous peptides modifications to computational libraries. Evaluation relies… read more here.
Keywords: aggregation; toxicity; model membranes; membrane interactions ... See more keywords
The interaction of steroids with phospholipid bilayers and membranes.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical reviews"
DOI: 10.1007/s12551-021-00918-2
Abstract: Steroids are critical for various physiological processes and used to treat inflammatory conditions. Steroids act by two distinct pathways. The genomic pathway is initiated by the steroid binding to nuclear receptors while the non-genomic pathway… read more here.
Keywords: steroid membrane; effect steroids; phospholipid bilayers; membrane interactions ... See more keywords
Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.02.025
Abstract: The formation of a mature myelin sheath in the vertebrate nervous system requires specific protein-membrane interactions. Several myelin-specific proteins are involved in stacking lipid membranes into multilayered structures around axons, and misregulation of these processes… read more here.
Keywords: protein; ionic strength; membrane interactions; membrane ... See more keywords
Imaging Flow Cytometry Illuminates New Dimensions of Amyloid Peptide-Membrane Interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical journal"
DOI: 10.1016/j.bpj.2020.01.018
Abstract: Membrane interactions of amyloidogenic proteins constitute central determinants both in protein aggregation as well as in amyloid cytotoxicity. Most reported studies of amyloid peptide-membrane interactions have employed model membrane systems combined with application of spectroscopy… read more here.
Keywords: amyloid peptide; imaging flow; 106 126; flow cytometry ... See more keywords
Effect of polyphenols-membrane interactions on the performance of membrane-based processes. A review
Sign Up to like & getrecommendations! Published in 2017 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2017.06.013
Abstract: Abstract Polyphenols have received a great attention in the last years due to growing evidence of their health-promoting activities and antioxidant characteristics. In this review, the effect of polyphenols-membrane interactions, phenolic-phenolic interactions or interactions with… read more here.
Keywords: membrane interactions; polyphenols membrane; effect polyphenols; performance ... See more keywords
Photocatalytic nanoparticles - From membrane interactions to antimicrobial and antiviral effects.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2021.102526
Abstract: As a result of increasing resistance among pathogens against antibiotics and anti-viral therapeutics, nanomaterials are attracting current interest as antimicrobial agents. Such materials offer triggered functionalities to combat challenging infections, based on either direct membrane… read more here.
Keywords: photocatalytic nanoparticles; antiviral effects; antimicrobial antiviral; interactions antimicrobial ... See more keywords
Investigating Daptomycin-Membrane Interactions Using Native MS and Fast Photochemical Oxidation of Peptides in Nanodiscs.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05222
Abstract: Daptomycin is a cyclic lipopeptide antibiotic that targets the lipid membrane of Gram-positive bacteria. Membrane fluidity and charge can affect daptomycin activity, but its mechanisms are poorly understood because it is challenging to study daptomycin… read more here.
Keywords: photochemical oxidation; fast photochemical; membrane interactions; oxidation peptides ... See more keywords
Peptide–Membrane Interactions Monitored by Fluorescence Lifetime Imaging: A Study Case of Transportan 10
Sign Up to like & getrecommendations! Published in 2021 at "Langmuir"
DOI: 10.1021/acs.langmuir.1c02392
Abstract: The interest on detailed analysis of peptide–membrane interactions is of great interest in both fundamental and applied sciences as these may relate to both functional and pathogenic events. Such interactions are highly dynamic and spatially… read more here.
Keywords: peptide membrane; microscopy; fluorescence; membrane interactions ... See more keywords
Structural characteristics and membrane interactions of tandem α-synuclein oligomers
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25133-0
Abstract: Pre-fibrillar oligomers of α-synuclein are thought to be pathogenic molecules leading to neurotoxicity associated with Parkinson’s disease and other neurodegenerative disorders. However, small oligomers are difficult to isolate for study. To gain better insight into… read more here.
Keywords: characteristics membrane; structural characteristics; synuclein oligomers; tandem synuclein ... See more keywords
Characterization of the membrane interactions of phospholipase Cγ reveals key features of the active enzyme
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abp9688
Abstract: PLCγ enzymes are autoinhibited in resting cells and form key components of intracellular signaling that are also linked to disease development. Insights into physiological and aberrant activation of PLCγ require understanding of an active, membrane-bound… read more here.
Keywords: interactions phospholipase; membrane interactions; characterization membrane; plc ... See more keywords