Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103978
Abstract: In the present work, the oxoaporphine alkaloid dicentrinone was isolated, for the first time, from leaves of Ocotea puberula (Lauraceae). This alkaloid exhibited antiparasitic activity against trypomastigote forms of Trypanosoma cruzi (IC50 of 16.4 ± 1.7 μM), similar… read more here.
Keywords: dicentrinone; cell membrane; puberula lauraceae; ocotea puberula ... See more keywords
The role of size, charge, and cholesterol of cell membrane models in interactions with graphene oxide.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2022.128661
Abstract: The growing in manufacturing and applications of graphene oxide (GO), a two-dimensional nanomaterial, highlights the need for a better understanding of its environmental impact and toxicity. This work investigates the interaction of GO with cell… read more here.
Keywords: size; membrane; cholesterol; cell ... See more keywords
Mitochondrial membrane models built from native lipid extracts: Interfacial and transport properties
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.910936
Abstract: The mitochondrion is an essential organelle enclosed by two membranes whose functionalities depend on their very specific protein and lipid compositions. Proteins from the outer mitochondrial membrane (OMM) are specialized in mitochondrial dynamics and mitophagy,… read more here.
Keywords: lipid extracts; membrane models; properties mitochondrial; models built ... See more keywords
Membrane Models and Experiments Suitable for Studies of the Cholesterol Bilayer Domains
Sign Up to like & getrecommendations! Published in 2023 at "Membranes"
DOI: 10.3390/membranes13030320
Abstract: Cholesterol (Chol) is an essential component of animal cell membranes and is most abundant in plasma membranes (PMs) where its concentration typically ranges from 10 to 30 mol%. However, in red blood cells and Schwann… read more here.
Keywords: mol; chol; membrane models; bilayer ... See more keywords