Optimization of an in Silico Protocol Using Probe Permeabilities to Identify Membrane Pan-Assay Interference Compounds
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DOI: 10.1021/acs.jcim.2c00372
Abstract: Membrane pan-assay interference compounds (PAINS) are a class of molecules that interact nonspecifically with lipid bilayers and alter their physicochemical properties. An early identification of these compounds avoids chasing false leads and the needless waste… read more here.
Keywords: assay interference; interference compounds; membrane pan; membrane ... See more keywords