Assessment of Mitochondrial Membrane Potential and NADH Redox State in Acute Brain Slices.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1266-8_14
Abstract: Brain is one of the most energy-demanding organs. Energy in the form of ATP is produced in brain cells predominantly in oxidative phosphorylation coupled to mitochondrial respiration. Any alteration of the mitochondrial metabolism or prolonged… read more here.
Keywords: acute brain; nadh; assessment mitochondrial; membrane potential ... See more keywords
Generation of membrane potential beyond the conceptual range of Donnan theory and Goldman-Hodgkin-Katz equation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biological Physics"
DOI: 10.1007/s10867-017-9454-7
Abstract: Donnan theory and Goldman-Hodgkin-Katz equation (GHK eq.) state that the nonzero membrane potential is generated by the asymmetric ion distribution between two solutions separated by a semipermeable membrane and/or by the continuous ion transport across… read more here.
Keywords: generation; donnan theory; theory goldman; membrane potential ... See more keywords
Mathematical expression of membrane potential based on Ling’s adsorption theory is approximately the same as the Goldman–Hodgkin–Katz equation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biological Physics"
DOI: 10.1007/s10867-018-9512-9
Abstract: The Goldman–Hodgkin–Katz equation (GHK equation), one of the most successful achievements of membrane theory in electrophysiology, can precisely predict the membrane potential. Its conceptual foundation lies in the idea that the transmembrane ion transport across… read more here.
Keywords: adsorption; goldman hodgkin; membrane potential; equation ... See more keywords
Dynamics of neurons in the pre-Bötzinger complex under magnetic flow effect
Sign Up to like & getrecommendations! Published in 2018 at "Nonlinear Dynamics"
DOI: 10.1007/s11071-018-4468-7
Abstract: Breathing is a complex rhythmic movement. The dynamics of neuron firing activity has important implications in understanding the causes of pathological respiratory rhythm. Studies on electrophysiology have shown that the internal and external bioelectricity of… read more here.
Keywords: direct alternating; effect; magnetic flow; membrane potential ... See more keywords
Erythrocyte plasma membrane potential: past and current methods for its measurement
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00603-5
Abstract: The plasma membrane functions both as a natural insulator and a diffusion barrier to the movement of ions. A wide variety of proteins transport and pump ions to generate concentration gradients that result in voltage… read more here.
Keywords: potential past; past current; erythrocyte plasma; membrane potential ... See more keywords
Effects of Serotonin Receptor Antagonist Methiothepin on Membrane Potential of Premotor Interneurons of Naïve and Learned Snails
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DOI: 10.1007/s12668-017-0498-8
Abstract: It was shown that the application of methiothepin, the antagonist of serotonin (5-HT) receptors, caused a decrease in the membrane potential of the high-threshold premotor interneurons LPa3 and RPa3 of the intact snails and its… read more here.
Keywords: membrane potential; application; methiothepin; premotor interneurons ... See more keywords
In vitro 4-Aryloxy-7-chloroquinoline derivatives are effective in mono- and combined therapy against Leishmania donovani and induce mitocondrial membrane potential disruption.
Sign Up to like & getrecommendations! Published in 2018 at "Acta tropica"
DOI: 10.1016/j.actatropica.2018.03.023
Abstract: The present study evaluates in vitro the effect of two synthetic compounds of the 7-chloro-4-aryloxyquinoline series, QI (C17H12ClNO3) and QII (C18H15ClN4O2S), on Leishmania donovani parasites. The results obtained demonstrate that these compounds are able to… read more here.
Keywords: effect; donovani; membrane potential; leishmania donovani ... See more keywords
Factors affecting staining to discriminate between bull sperm with greater and lesser mitochondrial membrane potential.
Sign Up to like & getrecommendations! Published in 2018 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.12.007
Abstract: The sperm mitochondrial membrane potential (MMP) is usually evaluated using the JC-1 dye. This study aimed to verify the effect of incubation temperature (25 °C or 38 °C), incubation time (10, 30, and 45 min), JC-1 stain concentration… read more here.
Keywords: hmmp; incubation; min; membrane potential ... See more keywords
Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.135
Abstract: Molecular hydrogen (H2) is recognized as a medical gas applicable to numerous diseases including neurodegenerative diseases, metabolic disorders, and rheumatoid arthritis. Although the efficacy of H2 is reportedly attributed to its scavenging capability against the… read more here.
Keywords: electron; membrane potential; mitochondrial membrane; superoxide generation ... See more keywords
"Funny" channels in cardiac mitochondria modulate membrane potential and oxygen consumption.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.033
Abstract: The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by a family of four genes (HCN1-4). All isoforms are expressed in the heart, HCN4 being the most abundant in the sinoatrial node (SAN). HCN channels are… read more here.
Keywords: mitochondria; hcn channels; oxygen consumption; membrane potential ... See more keywords
New imidazoles cause cellular toxicity by impairing redox balance, mitochondrial membrane potential, and modulation of HIF-1α expression.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.059
Abstract: BACKGROUND Our previous reports demonstrated the prospects of a new series of imidazoles as a source of alternative anti-parasite treatments, thus warranting further studies that include toxicity profiling. OBJECTIVE In this study, we evaluated three… read more here.
Keywords: cellular toxicity; toxicity; compound; membrane potential ... See more keywords