Abstract 5875: Rab37 mediates intracellular trafficking and membrane presentation of PD-1 in T cells to foster an immunosuppressive microenvironment in lung cancer
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DOI: 10.1158/1538-7445.am2023-5875
Abstract: Programmed cell death protein 1 (PD-1) expressed on the surface of CD8+ T cells is known as an immune checkpoint protein. High expression of PD-1 leads to T-cell dysfunction in the tumor microenvironment (TME). Our… read more here.
Keywords: rab37; membrane presentation; intracellular trafficking; membrane ... See more keywords