Quantitative Analysis of Membrane Receptor Trafficking Manipulated by Optogenetic Tools.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1258-3_2
Abstract: Membrane receptors play a crucial role in transmitting external signals inside cells. Signal molecule-bound receptors activate multiple downstream pathways, the dynamics of which are modulated by intracellular trafficking. A significant contribution of β-arrestin to intracellular… read more here.
Keywords: trafficking; quantitative analysis; receptor trafficking; membrane receptor ... See more keywords
Quantitative Microscopic Analysis of Plasma Membrane Receptor Dynamics in Living Plant Cells.
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DOI: 10.1007/978-1-4939-6813-8_10
Abstract: Plasma membrane-localized receptors are essential for cellular communication and signal transduction. In Arabidopsis thaliana, BRASSINOSTEROID INSENSITIVE1 (BRI1) is one of the receptors that is activated by binding to its ligand, the brassinosteroid (BR) hormone, at… read more here.
Keywords: microscopy; receptor dynamics; dynamics living; membrane receptor ... See more keywords
T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2203247119
Abstract: During immune surveillance, CD8 T cells scan the surface of antigen presenting cells using dynamic microvillar palpation and movements as well as by having their receptors pre-concentrated into patches. Here, we use real-time lattice light… read more here.
Keywords: membrane receptor; use distinct; cells use; distinct topographical ... See more keywords
Identification and characterization of a membrane receptor that binds to human STC1
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DOI: 10.26508/lsa.202201497
Abstract: A study using TriCEPS-based ligand–receptor methodology and surface plasmon resonance assays identified that human stanniocalcin-1 binds to insulin-like growth factor-2 receptors in human leukemia monocytic cells with high affinity. Stanniocalcin-1 (STC1) is a hypocalcemic hormone… read more here.
Keywords: membrane receptor; methodology; affinity; igf2r mpri ... See more keywords
The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?
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DOI: 10.3390/molecules27165292
Abstract: The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane receptor specifically activated by bile acids. A series of evidence shows that TGR5 induces protein kinase B (AKT), nuclear factor kappa-B (NF-κB),… read more here.
Keywords: membrane receptor; tgr5; friend foe; receptor ... See more keywords