Membrane Shape Remodeling by Protein Crowding.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.04.029
Abstract: The steric repulsion between proteins on biological membranes is one of the most generic mechanisms that cause membrane shape changes. We present a minimal model where a spontaneous curvature is induced by asymmetric protein crowding.… read more here.
Keywords: protein crowding; shape remodeling; membrane shape;
Membrane shape-mediated wave propagation of cortical protein dynamics
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-02469-1
Abstract: Immune cells exhibit stimulation-dependent traveling waves in the cortex, much faster than typical cortical actin waves. These waves reflect rhythmic assembly of both actin machinery and peripheral membrane proteins such as F-BAR domain-containing proteins. Combining… read more here.
Keywords: protein; propagation; membrane shape; traveling waves ... See more keywords
DGKα, Bridging Membrane Shape Changes with Specific Molecular Species of DAG/PA: Implications in Cancer and Immunosurveillance
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14215259
Abstract: Simple Summary DGKα is being considered as a target in immunotherapy. An advantage of targeting this enzyme is that it potentially has a dual role, i.e., it would both decrease the proliferation of cancer cells… read more here.
Keywords: membrane shape; role; biology; cancer ... See more keywords