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Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109542
Abstract: The target of rapamycin complex 1 (TORC1) protein kinase is activated by nutrients and controls nutrient uptake via the membrane trafficking of various nutrient permeases. However, its molecular mechanisms remain elusive. Cholesterol (ergosterol in yeast)…
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Keywords:
membrane trafficking;
tryptophan permease;
tat2;
activator vhr2 ... See more keywords
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Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108799
Abstract: The plethora of functions of glutamate in the brain are mediated by the complementary actions of ionotropic and metabotropic glutamate receptors (mGluRs). The ionotropic glutamate receptors carry most of the fast excitatory transmission, while mGluRs…
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Keywords:
membrane trafficking;
presynaptic postsynaptic;
transmission;
postsynaptic sites ... See more keywords
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Published in 2019 at "Trends in parasitology"
DOI: 10.1016/j.pt.2019.08.008
Abstract: Phosphoinositides (or phosphatidylinositol phosphates, PIPs) are low-abundance membrane phospholipids that act, in conjunction with their binding partners, as important constitutive signals defining biochemical organelle identity as well as membrane trafficking and signal transduction at eukaryotic…
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Keywords:
membrane trafficking;
parasitic protozoa;
binding proteins;
phosphoinositides binding ... See more keywords
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Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2020.1761354
Abstract: Abstract Study: Membrane trafficking process is significant for the complex and precise regulatory of the nervous system. Rab11, as a small GTPase of the Rab superfamily, controls endocytic vesicular trafficking to the cell surface after…
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Keywords:
membrane trafficking;
rab11;
nervous system;
neurodegenerative diseases ... See more keywords
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Published in 2024 at "Genetics"
DOI: 10.1093/genetics/iyae216
Abstract: Membrane trafficking is a conserved process required for import, export, movement, and distribution of proteins and other macromolecules within cells. The Caenorhabditis elegans NIMA-related kinases NEKL-2 (human NEK8/9) and NEKL-3 (human NEK6/7) are conserved regulators…
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Keywords:
tat phosphatidylserine;
flippase affects;
flippase;
rme ... See more keywords
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Published in 2018 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcy027
Abstract: The RAB GTPase is an evolutionarily conserved machinery component of membrane trafficking, which is the fundamental system for cell viability and higher order biological functions. The composition of RAB GTPases in each organism is closely…
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Keywords:
rab;
membrane trafficking;
rab gtpases;
plant ... See more keywords
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Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.238279
Abstract: ABSTRACT The retinal pigment epithelium (RPE) is a highly specialised pigmented monolayer sandwiched between the choroid and the photoreceptors in the retina. Key functions of the RPE include transport of nutrients to the neural retina,…
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Keywords:
retinal pigment;
membrane trafficking;
pigment epithelium;
glance ... See more keywords
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Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.252676
Abstract: Membrane trafficking is an essential cellular process conserved across all eukaryotes, which regulates the uptake or release of macromolecules from cells, the composition of cellular membranes and organelle biogenesis. It influences numerous aspects of cellular…
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Keywords:
membrane trafficking;
use subversion;
subversion membrane;
viral use ... See more keywords
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Published in 2024 at "Journal of Cell Science"
DOI: 10.1242/jcs.260943
Abstract: ABSTRACT Membrane trafficking, a fundamental cellular process encompassing the transport of molecules to specific organelles, endocytosis at the plasma membrane and protein secretion, is crucial for cellular homeostasis and signalling. Cancer cells adapt membrane trafficking…
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Keywords:
adaptations membrane;
cancer;
cancer tumorigenesis;
trafficking cancer ... See more keywords
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Published in 2024 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2024.1350097
Abstract: Breast cancer (BC) is the most common type of cancer in women, and remains one of the major causes of death in women worldwide. It is now well established that alterations in membrane trafficking are…
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Keywords:
cancer;
breast cancer;
progression;
trafficking alterations ... See more keywords
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Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00440
Abstract: Fragile X syndrome (FXS) is the leading monogenic cause of autism and intellectual disability. The disease arises through loss of fragile X mental retardation protein (FMRP), which normally exhibits peak expression levels in early-use critical…
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Keywords:
protein;
membrane trafficking;
synaptic remodeling;
fmrp ... See more keywords